Different types of condoms that exist for men

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Different types of condoms that exist for men

There is a condom for every need, taste and masculine measure

If there is an effective condom both to prevent unwanted pregnancies and to protect from sexually transmitted diseases, condoms are , however few people know the different types that exist.

Most condoms are made of latex, a material derived from rubber that is quite sensitive, so they can adjust to the size of the penis. In fact it is one of the different types of condoms for men that exist.




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According to the media The Republic, a study of the Spanish Association of Andrologá, mentioned that the member of the Spaniards measures about 13.58 centimeters in length, therefore must look for condoms that are of average size.


XL CONDOMS FOR GIVEN PENINS. It should be noted that not all penises are equal and that they exist of different thicknesses and lengths. Although latex condoms tend to stretch enough without breaking, they adapt to the size of each male member, it is also true that there are some men whose penis can be "privileged" and bothered by the standard size.

In fact, men whose penises measure more than 18 centimeters in erection, feel that almost all condoms squeeze a lot, especially the ring or ligament of the base, which causes them to have discomfort and pain with the consequent loss of erection .

In some cases, condoms become too tight that it is common for them to break through the friction of the intimate act.

For these males who are considered by many "fortunate" there are XL condoms, which are specially designed for members with a length of more than 18 centimeters in length and a thickness of more than 14 centimeters in circumference. A XL condom provides the same efficacy and safety in men with large size limbs, even those who do not exceed 18 cms. in length, are thicker than average.

It is very important to know that using the condom of the correct size will make the intimate relationship pleasant, maintain the erection and reduce the risk of breakage.



To know what measure is right for you, it is important that you know your proper size, since an XL condom in an average penis will slide, staying inside the couple's cavity and exposing themselves to pregnancies and diseases.

You want to know the correct measurement, you must measure it when the member is fully erect, the man must stand and must use a tape measure, never a rigid rule. The length is measured by placing the tip with the tape measure against the pubic symphysis and sliding to the tip of the urethra. So that you can measure the thickness, the tape measure is rolled in the thickest part of the penis.

In case the member measures between 12-14 cms. of the circumference and 15-20 cms. in length you should use an XL condom, while if you exceed these measures you should use the XXL.




TYPES OF CONDOMS FOR ALL THE PENES. Fortunately in the market there are countless condoms that can be adopted to meet the needs of both men and couples. Apart from the large sizes described above, there are some more common.

FLAVOR CONDOMS. They are ideal to practice oral sex as they are lubricated with gels of different flavors such as banana, strawberry, chocolate, chewing gum, mint, etc.

RETARDANT CONDOMS. They are special for those guys who finish very fast. They are a little thicker and may contain slightly anesthetic lubricant, with the aim of delaying ejaculation.

FINE CONDOMS. Unlike the previous ones, these are much thinner so they provoke a sensation very similar to as if it were not being used, but it should not be used in large penises because they can be broken.

STRETCHED CONDOMS. These are presented with reliefs (points, channels or grooves) to offer a double sensation to the couple.

ANNUAL CONDOMS. They are much stronger than traditional ones, which usually guarantee greater safety in the anal act.

CONDOMS WITH SPERMICIDES. These condoms contain a spermicidal gel that reduces the mobility of the sperm that could "escape", in order to further reduce the chances of pregnancy.

Condoms, types and varieties

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Condoms, types and varieties

In terms of sexuality, there are many elements and devices that arise every day both to protect, and to keep the spark of love burning, in the first case, one of those elements are condoms.

As its name implies, condoms seek to protect people from contracting sexually transmitted diseases or unwanted pregnancies. However, the big brands that supply condoms all the time are looking to innovate and not only offer the protection that their users need.




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Sexuality

Applications to improve sexual life as a couple

For this, KienyKe.com, made a compilation of the different types of condoms that can be found in the market and what is its specific function within the sexual life of man.

Classics

Classic condoms are those that have been known historically and that have a standard material and measurement. This type of condom is what seeks to simply provide protection to anyone who uses it, factors such as comfort and lubrication go into the background.

Latex free

In times when societies suffer from many diseases and allergies, the material used to make condoms could not be foreign. Latex allergy is more common than it seems and manifests itself through a burning sensation and irritation.

Latex-free condoms are a good option and they are here to stay. For its creation, instead of using the characteristic material, other types of elements are implemented.

Flavors

This type of condom is what it seeks is that in addition to protecting, it is generating a different sensation among those who wish to practice oral sex. The most common flavors are fruity, chocolate, vanilla and even menthol.

Retardants
Premature ejaculation is one of those problems that in addition to affecting sexuality, harms the self-esteem of people. The large condom providers have been concerned about this, and created condoms with a delaying action, keeping the enemy away from premature ejaculation.

Sexuality

Pegging: the new sexual practice

It is important to note that many claim that using them do not feel pleasure.

Anatomical

The anatomical ones are those that do not come of a predetermined size, but that adapt to the form and size of the penis. These are necessary in cases where men have curvature or anomalies in their limb.

Textures
These condoms are made up of points and lines that according to experts provide a greater sense of pleasure. Condoms with textures allow sex to be pleasurable for the couple.

Spermicides
Spermicidal condoms are considered the most effective to combat sexually transmitted diseases and unwanted pregnancies. The condom what it does is to damage the sperm avoiding pregnancies in case of rupture.

Types of condoms: those of flavors, textures and even the kill-sperm

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Types of condoms: those of flavors, textures and even the kill-sperm

Sexuality can be categorized as an instinct or a basic need for many. In addition, the union can represent different things such as sharing a bond with another person, releasing stress, receiving pleasure or having fun. No matter the reason that leads to the practice of sex, the important thing is that you do it responsibly. And to begin to clear doubts, here I tell you about the types of condoms that exist in the market.




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For now, I already saved you the pain of going to ask a condom or sex shop and I brought the most relevant information so you know the options and stop pretexting to take care of and take care of the person with you.

Types of condoms

    Male latex

This is the typical condom that we have all had in our hands or seen in a pharmacy dresser and has several presentations that aim to meet the tastes of the majority. Although it is only 99% effective against pregnancies, the risk is much lower than not using it, also, as I said, it has several options that suit your tastes:

•     Flavors
•     Textured
•     Fluorescents
•     Extra thin

    Feminine

Yes, they do exist and are made of polyurethane, which is a more resistant and less irritating material than latex. Its effectiveness is between 79 and 98% and can even be placed a few hours before having sex. I mean, the responsibility of the condom is always awarded to man; however, this option gives women more decision power and protection.

    Polyurethane: for those allergic to latex

Because in this safe sex there are no pretexts, within the types of condoms highlights the polyurethane condom (male or female), the best option for those suffering from latex allergy. Maybe you thought it was a lie to not use a condom, but it does exist and in severe cases it can cause suffocation.

It is thinner, but more resistant than latex, so, with or without allergy, it is worth knowing that this option exists .

    With spermicide

The condom is used to prevent STDs and unwanted pregnancies, but if you want to reinforce your protection to avoid having children, these condoms are covered with spermicide to kill the little friends before they even start the mission. Its effectiveness is around 97% and 99%.

    Retardant

That's right, if your problem is not reaching the goal of duration, the use of a delaying condom can help you. The presentation is the same, but it has an anesthetic on the inside to "feel a little less" and you can achieve your mission.

    Accelerators for her

And then, if they can be delayed, it would not hurt a little help so that they can get there faster, so, within the types of condoms is the accelerator. Actually it is a mixture of other products, brand depends, these condoms have texture at the tip and a lubricant is added that changes temperature, heating to facilitate the climax.

    Condoms and lubricants

This is an important section, since many condoms are already lubricated, but it may not be enough or, maybe you like to play for a while and lubricants are a perfect option to do so.

They are based on water and silicone ranging from the simplest flavors to those that are heated or cooled to exalt your pleasure and your senses. But, beyond that, what you have to take into account is that the lubricant is not oil-based , as it can damage the condom and even break it and thus, the exposure and risk are high.

Now you know what types of condoms and stimulants exist. Needless to say why it is absolutely necessary that you use condoms and do not take sex lightly, since beyond an unwanted pregnancy, an unprotected encounter can change your life by directly and irremediably impacting your health.

What I can tell you is that condoms are not only protection, they are also the perfect tool to avoid falling into monotony. You know, the idea is "turn on and surprise your partner". So, which one is your favorite? Do you already know which one to choose for your night of passion?

Types of condoms - Know all available varieties

• LifeStyles Ultra Sensitive Condoms, 40ct

Types of condoms - Know all available varieties

Surely you have never used a condom because of the "difference" between using it and not using it ... This as you know is very risky, as long as no other contraceptive has been used, so you should not do it again. Secondly, you probably do not know the giant variety of types of condoms that we can currently buy !!

With this variety of condoms you will notice different and exciting sensations, both you and your partner. Keep reading and learn how to enjoy more with a condom than without it, or at least try it.




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Types of Condoms

In this article we focus on the types of male condoms.

The difference between having sex with a condom and without it, is reason enough for some people not to use it, falling into the risk of an unwanted pregnancy, and of course, of contracting any sexually transmitted disease.

Some brands and manufacturers have gone to work to try that this does not happen, and have released hundreds of different types of condoms. I'm going to classify these condoms in 8 different categories. How is it logical, not all brands sell all, or at the same price, but in the market we have available at least this variety that I leave.

•     Condoms with temperature effect
•     Extra fine condoms
•     Aromatic condoms
•     Condoms with retardant effect
•     Embossed condoms (textured)
•     Fluorescent condoms
•     Flavor condoms
•     Extra safe condoms

In addition to these types of condoms that are more oriented to pleasure, to the sexual "game" ... we can find 2 other groups more oriented to the efficacy or necessity, but that do not contribute anything extra "pleasant" to the sexual act.

•     Condoms with spermicides
•     Hypoallergenic condoms

Temperature effect

Surely you have seen some adverts of lubricants with heat effect and cold effect ... In Durex for example, we have these really incredible lubricants available !!

Well, condoms with temperature effect have the same function. They have applied a thermal lubricant that together with friction and humidity generates a really hot and cold effect for both you and your partner !!

It is a really different feeling that gives an original touch to the sexual relationship and that I encourage you to try either through these condoms, or using the lubricant that I mentioned earlier.

You can find it for example in control condoms (Control Energy) and Durex condoms (Heat effect), Trojan condoms (Trojan Fire & Ice), Sico condoms (Sico Hot Pleasure) then I leave you links to buy them at an unbeatable price!

Extra Fine

As you know, one of the main disadvantages of using a condom is the lack of sensitivity compared to having sex without it. With this type of condoms this is solved !!

They have created an ultra-thin latex that barely reduces sensitivity during sexual intercourse, and will give you the impression of having sex without a condom on. In addition, they have achieved the same security as with the normal condom, so do not worry if it can be broken !! Logically it will influence if you put the condom correctly and the use you give it.

There is a wide variety of manufacturers that market this type of condom.

We have Durex Condoms (Durex Sensitive, Real Feel Durex), Condoms Control (Ultra Feel), Trojan Condoms (Trojan Sensitivity Ultra Thin / Skin Nude), Condoms Sico (Sensitive, Ultra Sense) ...

Aromatics

Sometimes the smell during a sexual relationship is somewhat uncomfortable and even unpleasant. That's why they have invented condoms with aromas that hide any bad smell , and allow you to have sex with total comfort.

You can find condoms with aroma of chocolate, mint, natural tea, apple, banana, rose, caramel, coconut, melon, tutti-frutti, coke, vanilla, cream, watermelon ....

As you can see, the amount of options you have to try and give a different touch to each sexual relationship is huge!

Retardant Effect

This is perhaps one of the most exciting categories and that you will like the most. There are quite a few people who have premature ejaculation, and many others who do not, but who will surely love to take longer to finish ...

Well with these condoms you have your solution! They have developed condoms that contain an internal lubricant with a substance (benzocaine) that prolongs and delays the climax .

These condoms are brutal, and I strongly encourage you to try them! You will prolong much more the pleasure of yours, as of your partner, and the sex will be longer !!

A large variety of brands market them. Dúrex Condoms ( Prolonging Pleasure, Mutual Climax), Control Condoms (Control Non Stop, Control Retard), Trojan Condoms (Trojan Extended), Sico Condoms (Sico Mutual Climax).

Textured

Textured condoms are those that have stretch marks, dots , and other reliefs on the surface of the condom . These condoms are designed to try to simulate the touch of the penis, since it is not completely smooth.

With these condoms your partner will hallucinate with pleasure, and feel a much more fun feeling than with a totally smooth condom. Each brand manufactures condoms with different textures and with totally original reliefs, so we encourage you to try and choose the one that you and your partner like the most!

Control Condoms (Touch & Feel, Non Stop), Durex Condoms (Mutual Climax, Pleasure Me / Dame Pleasure, Intense), Trojan Condoms (Textured Ecstasy), Sico Condoms (Mutual Climax, Pleasure Feel, Pearl)

Fluorescents

If you want to spend an original time in the dark, opt for fluorescent condoms. These condoms shine in the dark, and they can be really fun. They protect in the same way as a normal condom, so you can use them safely.

They are available in brands such as Glow or Prudence condoms .

Flavors

To avoid the unpleasant taste of latex when practicing oral sex, male condoms are commercialized with a great variety of flavors.

The condoms of flavors are present in most of the most important brands, and are also usually accompanied by characteristic colors, to easily differentiate the flavors.

These condoms have exactly the same guarantees and protection as a normal condom, so they can be used safely.

The flavors of condoms have evolved, from the simplest to some really extravagant. Almost all the brands that have flavored condoms market a very similar range of flavors, some of them being present, such as chocolate, strawberry, banana, apple, orange, pineapple, mint, coconut ... and even some more striking as a cola flavor, or flavor to chewing gum.

We can find flavors in Durex condoms (Saboreame, Tropical), Control condoms (Fussion), Sico condoms (Tropical Feel). In this case, Trojan condoms do not sell flavored condoms.

Extra Insurance

If you are amateurs or want to practice anal sex, keep in mind that you must do it with a condom to avoid any infection. However, anal sex usually needs more lubrication. In addition, being narrower than vaginal sex, rubbing with the condom is stronger and could break it.

That is why extra strong or extra safe condoms have been devised, which provide extra protection and lubrication. With these condoms you can practice anal sex with total tranquility and comfort.

For those who want to have vaginal sex but still be uneasy with a normal condom, they can logically also use this type of condom if they feel more secure.

This type of condom is sold by almost all brands. We can find Durex condoms (Extra Safe), Control condoms (Control Forte), Trojan condoms (extra strong), Sico condoms (Safety).

With spermicides

Spermicides are chemical substances that kill sperm , or reduce their movement to prevent them from reaching the egg. Its function is to complement some contraceptive method to give extra protection against an unwanted pregnancy.

In the case of condoms with spermicides, condoms bring inside these substances that kill the ejaculated semen to avoid a pregnancy in the event that the condom comes out or breaks.

Although it seems a good idea, it is not a fact that is recommended, in fact it is used less and less, since the condom placed in the right way has a very high effective on its own, and spermicides can cause allergies or irritations in enough people since their chemical compounds are not tolerable all over the world.

Hypoallergenic

Hypoallergenic condoms are those intended for people allergic to latex . As we commented in the article on the condom, there are alternatives in several compounds such as polyurethane, pig guts, or polyisoprene.

The advantage of these condoms, such as polyisoprene, is that the material is extremely thin, and the feeling is practically the same as if you were not wearing any prophylactic.

The big brands have condoms of this type, being able to find condoms Durex (Real Feel), condoms Control (Latex Free), condoms Trojan (Supra Bareskin / Skin Nude), condoms Sico (Real Feel, Thermaxx Skin).

As you can see, there is a wide variety of condoms, from the simplest to the most sophisticated. Our recommendation is that you should try all of them and enjoy each one in your own way.
More than seeing them as an impediment, try to see them as a sex toy that gives you a plus in your relationships.

Video about an ad for types of condoms

I leave you a curious announcement in which you can see how the big brands make different types of condoms that fall into several categories, for example the Durex Mutual Climax, which have extra lubrication, stretch marks (textured) for your partner, and retardant effect for you…

Do you know the 7 types of condoms?

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Do you know the 7 types of condoms?

If you do not know what is the difference between each condom, here we clarify the types of condoms that exist so you can choose the best for each occasion.

To date, condoms are the only ones that protect us from sexually transmitted diseases, such as HIV, chlamydia, bacteria, parasites, fungi and viruses.

In addition to covering the basic need of our casual encounters, pregnancy. We are in 2016 and we definitely need to have a full and safe sex life.




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You may also like: Men who refuse to use a condom are less attractive

    The classic

All brands of condoms have a line of these, have a standard size and thickness, focus on simply providing protection. They exist with or without lubrication, so check the box well.

    Ultra Slim

These give you greater feeling and can be so thin that it would seem to be not using any. This is ideal to have security and feel more.

    Delaying effect

For those who want to delay ejaculation this is your condom. They have a special lubricant with Benzocaine, it works as a small sedative that diminishes a little the sensations, allowing to arrive in more time at climax.

    Textured

They can have textures such as stitches or stretch marks that stimulate both women and men during penetration.

    Flavored

There is so much variety of flavors in condoms and they allow you to have oral stimulation. For example, Sico has one called Tropical Feel with an orange, strawberry and banana flavor.

    Latex-free condoms

For those people who are allergic to latex, there are polyurethane condoms. Almost all brands have their version without latex, so ask.

    In hot

These condoms have a special lubricant that gives a sensation of heat on contact. There are some like the Sico Hot Pleasure , which combines the texture with lubricant in heat, it would be worth trying.

6 types of condoms you should know

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6 types of condoms you should know

The condom is the most used contraceptive method currently. Its importance lies in the fact that it can not only prevent unwanted pregnancies, it also prevents the transmission of Sexually Transmitted Diseases (STDs).
With a 99 percent effectiveness, there are many types and brands of condoms on the market, here we present some types of condoms in the voice of the psychologist and sexologist Ariadna Pulido de Doctoralia.




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1. Latex

It is the most common type of condom and used to be the lowest price in the market. Its effectiveness is 99 percent. Some people are allergic to this material, so watch for signs such as redness, itching or burning.

2. Silicone

Silicon condoms are used by people with sensitive skin.
The sensitivity of this material is similar to that of latex but has presented less allergic reactions. Its effectiveness is the same.

3. Textured

These condoms usually have relief or various textures to increase both male and female pleasure. Its effectiveness is also 99 percent, its use depends on what each person wants at the time of sexual intercourse.

4. Feminine
This type of condom is rarely used because its price can be up to seven times higher than that of male condoms. Your placement may be hours before intercourse and may be used for more than one intercourse without removal.

5. Different flavors

Condoms with flavor and aroma are recommended and generally used for oral sex. These prevent STDs that can be transmitted orally. They are used for a greater sexual romp.

6. Of different sizes

Some brands present their condoms by sizes small, medium, large and extra large. Knowing the correct size of condoms you should use could help prevent accidents such as condom breakage.

Sizes on condoms, how to know which one is yours

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Sizes on condoms, how to know which one is yours

It is true that condoms are elastic and stretch a lot, but we must take special care, because condoms exert some pressure on the penis, especially the condom ligament, something that can be painful for men, and all for not use the right size, that's why today we're going to show you the sizes in the condoms .

The male genitalia have different sizes, which is why in recent years more tight condoms and larger condoms have appeared, in order for men to have the right product for the size of their penis.




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Wisdom That Helps: According to the National Center for the Prevention and Control of HIV / AIDS (Censida), since the late 80's the use of condoms has gradually increased among the young population; while in 1988 it was barely used by 6%, now the average is over 70%

How to know what is the correct size?

There are 6 different sizes in condoms , traditionally the sizes are grouped into three types, which are: small, medium and large. But there are three different subcategories that can help you find the ideal size for your penis. So we have that the sizes are XS, S, M, L, XL and XXL. Using condoms of your correct size will allow you to enjoy sex more comfortable and safe, you will get the perfect fit. If the condom is loose you will slip, but if you squeeze too much will cause discomfort that will prevent you from enjoying a pleasant relationship, as who says ... not very, very and not so, so.

The measure that really matters is the circumference, and the length may not be as important, since the condoms are unrolled, you must measure yourself with the penis in erection and you must measure the thickest part of your penis.

Sizes in condoms:

•     Size XS: It is for penises between 5-10 cm. of circumference and 8-16cm. of length
•     Size S: For penises between 10-11 cm. of circumference and 10-18 cm. of length.
•     Size M: Cocks between 11-11.5 cm. of circumference and 13-19 cm. of length.
•     Size L: For penises between 11.5-12 cm. of circumference and 14-20 cm. of length.
•     Size XL: For penises between 12-14 cm. of circumference and 15-20 cm. of length.
•     Size XXL: For penises of 14 or more cm in circumference and 15-20 cm. in length, or more.

How to get the measure:

It is common for men to measure themselves incorrectly, sometimes because of the male ego and other times because they do not measure themselves well. But having the right condom will allow you comfort, safety and pleasure.

To measure the length put the measuring tape and stand with the penis erect and in a position parallel to the floor, measure your penis along the tape supporting the symphysis pubis. To measure the thickness do it by the central part of the trunk of the penis, rolling the tape measure starting from the side of the penis that is towards the ground. Another way to know which is your ideal size is buying and testing the different sizes in the condoms of the store and choose those that best fit your measurements.

Some condoms:

If you find it difficult to find your size because they do not sell it at the pharmacy, you can always use your nearest condom. The condoms are places with a strong tendency for sexual health, unlike the SexShop that tend to have a tendency to play and eroticism.

Do you know how many types of condoms exist?

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Do you know how many types of condoms exist?

This night is the night! Finally, you will meet your partner in bed, so you decide to be cautious and have condoms at hand. You enter the pharmacy, find the condom hall and face the great dilemma of choosing which package to buy. Do you know how many types of condoms exist?




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Wisdom That Helps: According to the Mexican Youth Institute (IMJ) Currently 36% of young Mexicans do not use a condom in their sexual relations


Your parents, teachers, friends and even the media repeated to you that you should be responsible for sex and that the condom is the best way to prevent sexually transmitted infections and unwanted pregnancies; however, no one told you there were several types of condoms.

Yes of course, you are aware that there are female condoms and that male condoms can come in various sizes, but ... fluorescent, flavored and textured?

To clear your doubts and next time you find it easier to buy them, here we present the different types of condom.


Do you know how many types of condoms exist?

•     Change of temperature . These condoms contain a thermal lubricant that will raise the temperature of your sexual encounter and provide you with greater pleasure.
•     Fluorescent These condoms are photosensitive, so they glow in the dark. They are ideal to give a fun touch to your nights of passion.
•     Flavors If your partner and you like oral sex, you can not stop trying these condoms, they will give an exotic touch to your meetings.
•     Textured These condoms have become popular in recent times, because the texture of the surface will raise your sensitivity and allow you to enjoy more of your partner. This variety is usually recommended for women who say sex is more enjoyable without a condom.
•     Lubricant These are the most used condoms and their only purpose is to facilitate penetration.
•     Retardant Although few men accept it, many suffer from premature ejaculation , which is why these condoms were created that contain anesthetic substances that delay orgasm.
•     Spermicide. These condoms contain a substance, both inside and on the surface, that nullifies the function of sperm.
•     Aromatics Like flavored condoms and fluorescents, aromatics will give a special touch to your encounters. You can even choose a scent that will help you relax.
•     With vibrator . Although they are more expensive than other condoms, this variety guarantees you reach the climax, since its vibrating ring stimulates the clitoris during penetration.
•     Extra thin . Its very name says, these condoms are made with the thinnest latex exists, so the two will have greater sensitivity during sex. And do not worry, the fact that they are thin does not mean they break easily.

The 9 best types of condoms

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The 9 best types of condoms

1. Fluorescents


They shine in the dark, to guide you when the lights go out.

2. Flavors


They are perfect for oral sex, remember that who should choose the flavor is you, since you are the one that will delight in trying it.




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3. Textured


If you are the one who prefers sex without a condom, because you think it feels better, you can use this type of condom, as its name says it is textured simulating a penis.

4. With lubricant


Sometimes a little help is needed and with lubricant it will be easier to penetrate.

5. With spermicide


This type of condom contains spermicide on the surface and inside the condom, this cancels the function of the sperm.

6. With retardant


Prevent premature ejaculation that affects a large percentage of men. They have anesthetic substances, which reduce sensitivity, thus delaying the moment of climax for them.

7. Aromatics


Use them to play with your partner, this encourages the sexual relationship because it is something out of the routine.

8. With vibrator


They have a small device that turns the condom into a temporary vibrator. It would be worth buying to try it, well, more than anything, to feel it. The cost is higher than that of a normal condom.

9. Extra fines


They are very thin, therefore there will be more sensitivity in the sexual act.

Biotinidase Deficiency

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Biotinidase Deficiency

DEFICIENCY OF BIOTINIDASE is a treatable metabolic disease in which the body is unable to obtain the vitamin BIOTIN in the proper way. Early diagnosis with initiation of treatment even in the first months of life assures the baby a normal life without any symptoms of the disease.

The human body is very complex. Within it, thousands of chemical reactions occur involving the food we eat, the air we breathe, our adaptation to the environment, and our growth and development. Some of these chemical reactions allow food to be processed or metabolized for use by our body.

Enzymes are special proteins produced by the body to allow chemical reactions to occur. Enzymes with adequate function are called active or with activity. Some enzymes need vitamins to be active. Often a single active enzyme acts in the supply of various substances that our body needs.



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Sometimes the body does not produce a sufficient enzyme or the enzyme that is manufactured does not work properly. This causes the enzyme to have a reduction of its activity and does not function as it should. Other chemical reactions that depend on this enzyme may also be impaired.

If the activity of the enzyme is less than 10% of its normal activity it is considered deficient. Normally enzymatic deficiencies entail medical problems. Health problems resulting from a deficient enzyme are called metabolic diseases because the metabolism or chemical processes of the body is not happening normally.

Biotinidase is an important enzyme in our body. People with biotinidase deficiency do not have sufficient biotinidase activity (Figure 01). Individuals with biotinidase deficiency have enzyme activity less than 10% of normal and sometimes have no activity. These individuals with biotinidase activity less than 10% of the normal mean have profound biotinidase deficiency. Parents of children with biotinidase deficiency have approximately 50% of normal biotinidase activity, which is sufficient to prevent health problems. People who have biotinidase activity between 10 and 30% of normal have partial deficiency of biotinidase. Both forms require treatment. The figure below illustrates the percentages of biotinidase activity in blood and compares them with normal activity.

Biotinidase is an important enzyme in the biotin cycle, the chain of chemical reactions involved in the use and reuse of vitamin biotin. An important task of biotinidase is to separate or release biotin from food proteins. In addition, biotinidase allows the body to recycle biotin several times so there is no need to consume large amounts of this vitamin in our daily diet.

Free biotin is required so that a group of enzymes called carboxylases work perfectly. Carboxylases are important in the metabolism of some fats, carbohydrates and proteins. In order for the inactive carboxylase to become active, the free biotin must be attached to the amino acid, lysine, at a specific site of the inactive carboxylase.

Eventually the carboxylases are degraded, but the biotin is attached to the lysine. This biotin-lysine complex is known as biocitin. Biocitin is normally degraded by biotinidase in free biotin and lysine. In this way, biotin is recycled and can be reused by the carboxylases.

When biotinidase activity is deficient the biotin that is contained in food can not be used by the carboxylases. Carboxylases are incapable of performing their normal functions. Without proper biotinidase activity, the body needs large amounts of free biotin, more than is consumed in a normal diet. When there is no biotin available in the body, health problems begin to appear.

A frequent question is: how does biotinidase deficiency affect my child?

WITHOUT TREATMENT

Without the ingestion of biotin, children with biotinidase deficiency may develop one or more of the following symptoms:

•     Alopecia (hair loss) .
•     Delayed development.
•     Hypotonia.
•     Aciduria lactic.
•     Convulsions .
•     Skin rashes / skin infections.
•     Ataxia.
•     Conjunctivitis.
•     Loss of hearing.
•     Lethargy.
•     Mild hyperammonemia.
•     Breathing problems.
•     Vision problems.
•     With the.
•     Difficulty feeding.
•     Fungal infections.
•     Hepatomegaly (enlarged liver).
•     Speech problems.
•     Splenomegaly (enlargement of the spleen).

Symptoms usually manifest between the third and sixth month of life, but may appear earlier, for example, at one week of life or later at ten years of age. The number of symptoms a child develops and the seriousness of the disorder can vary from child to child, even though they are from the same family.

Initial symptoms of biotinidase deficiency usually include convulsions of various types, especially myoclonic seizures, and hypotonia. These symptoms are not unique to biotinidase deficiency, but are a clue to investigate it. Other symptoms that occur early include tachypnea (rapid breathing), hyperventilation, stridor (noisy breathing), apnea, skin rashes, seborrhea or atopic dermatitis, partial or complete hair loss, conjunctivitis, delayed mental development. Ataxia and developmental delay are observed in the course of the disease. The immune system apparently alters and viral and bacterial infections can occur in untreated children. Hearing loss is usually sensorineural and vision problems, primarily optic atrophy, may arise. Metabolites can accumulate abnormally causing permanent damage to organs such as brain, skin, ear and eyes. Children who do not receive adequate treatment can die early.

According to research by Dr. Barry Wolf * 95% of children who have some type of symptom also have some degree of hearing loss. So if your child / patient has any of the symptoms listed above, you should do a hearing test. If your child did not present any symptoms and was medicated in the first weeks of life the examination is not necessary.

Deficiency of undiagnosed and treated biotinidase may be considered one of the causes of Sudden Infant Death Syndrome, although more information is needed in this area.

WITH TREATMENT:

All children who developed the symptoms of biotinidase deficiency had significant and rapid improvements with the onset of biotin ingestion.

Children who underwent the neonatal screening test (Pezinho Test) and started treatment early to date did not develop any of the symptoms.

HOW IS DEFICIENCY DIAGNOSED?

Diagnosis of BIOTINIDASE DEFICIENCY is performed through the neonatal screening test, better known as Pezinho Test. With an early diagnosis the treatment can be initiated even in the first month of life, thus preventing symptoms from manifesting.

WHAT IS THE SCAN TEST?

It is an analytical method valid for the identification of some individuals, of a certain population, with high probability of manifesting a particular disease. When the neonatal screening test presents a change, another analytical procedure is necessary to provide data that allow a differential diagnosis to be made. Therefore, the result of the screening test, alone, is not definitive.

HOW IS MY BABY TEST MADE?

A drop of blood is obtained from the baby's heel, a vascularized and almost painless zone, and impregnated on a special filter paper. After the blood has dried, the sample can be sent by the Post Office to a specialized laboratory. A "pick" of the paper with the blood is removed, and through biochemical procedures the activity of the enzyme is "measured" by the color intensity present at the end of the reaction. The absence of color or staining below the standards used defines the result of the screening: absence or decrease of biotinidase activity.

CLINICAL DIAGNOSIS IS POSSIBLE?

Yes; In the most severe cases, the symptoms appear after six months. As it is a disease that is difficult to recognize by the physician (its symptoms are confused with those of several other pathologies) the clinical diagnosis may not be made and the consequences can be very serious.

HOW TO ASSURE THAT THE TEST IS RELIABLE?

The laboratory works with biological variables. How to ensure that an airplane will not fall or that we will not have accidents on a trip? A general limitation of any screening test is that not all affected individuals will be identified, but almost 100% will be identified. In general, false-positive results (not confirmed in subsequent tests) are more likely than false-negative results (presence of disease and result expressed as normal).

IF THE RESULT HAS TAKEN PARTIAL ACTIVITY THE TEST MUST BE REFURBISHED?

The screening test should ALWAYS be confirmed. Biotinidase is an enzyme that is sensitive to heat and time. The first confirmation can be made on filter paper. If the confirmed activity is confirmed, the confirmatory test must be done in the serum (collection of the arm), and this should be sent to the frozen laboratory.

WHAT IF YOU HAVE SUSTAINED ACTIVITY?

The analysis should be done directly in the serum and as soon as possible. Remember that of all diseases of the foot test, it is the easiest, cheap and effective treatment.

HOW IS BIOTINIDASE DEFICIENCY TREATED?

People with BIOTINIDASE DEFICIENCY are unable to get BIOTIN in their daily diet. For a successful treatment it is necessary to take 5 to 20 mg of BIOTIN FREE daily, orally for an indefinite time.

Children with BIOTINIDASE DEFICIENCY who initiate treatment early do not develop symptoms related to this disorder. It is a lifelong treatment and should not be interrupted.

Biotin can be obtained from handling pharmacies. The price of biotin can vary from state to state. There have already been price variations of up to 650% from one pharmacy to another, in different cities. Since it is a permanent treatment, it is worth consulting in several pharmacies, remembering that care must be taken to acquire biotin in a well-accredited pharmacy.

No serious side effects from biotin ingestion are known, despite the limited amount of information available on continued use of the vitamin. With the progress of children treated with biotin, doctors are gaining a better understanding of the need for biotin in the body.

Biotin is usually handled and delivered to the patient in capsules or tablets. Do not use tablets. Use the capsules that can be unlocked and added in the baby's milk or in your food. In the case of mothers who are breastfeeding their babies, one should manually remove the milk from the breast and dissolve the biotin in a small amount of it. Make sure the baby is ingesting all the medicine. The most practical thing is to dissolve the contents of the capsule and to give in a spoon or cup with milk, juice or water. Bottle feeding is not a good option as the powder can be trapped in the bottle nozzle. Liquid biotin should not be administered as it may result in an inadequate dosage. Usually biotin is administered once daily.

WHAT CAUSES BIOTINIDASE DISABILITY?

Children with biotinidase deficiency received the genetic inheritance of two genes for biotinidase deficiency, one from the father and one from the mother. It is not caused by something that either parent did before or after the baby's birth.

The instructions for the body to make the biotinidase enzyme function are encoded in a pair of genes. Genes are tiny units of genetic information that tell our body cells how to do certain jobs, such as enzymes. We all possess a unique set of 50,000 to 100,000 different gene pairs, each encoded to exert a function. The instructions are received from a single code in the DNA, the material with which the genes are made. If there is some kind of error in the instructions the gene product will not work properly.

Genes are organized into small groups called chromosomes. In each chromosome there are between 2,000 and 5,000 genes. Each cell has 23 pairs of chromosomes, one member of each pair is inherited from the parent and one member inherited from the parent. There are 22 pairs of autosomes (non-sex chromosomes) and 01 pair of sex chromosomes (which determines whether the person is a man or a woman).

Because the chromosomes come in pairs, the genes also come in pairs. One copy of each gene is inherited from the mother and one from the father. Although a child divides half of its genes with each parent, it is still different from them, since it receives the other half of the other parent. Brothers and sisters also have their own combination because they never inherit exactly the same combination of genes unless they are identical twins.

People with biotinidase deficiency receive a defective biotinidase gene from the father and mother. As they have no copies of the normal gene the biotinidase activity of their body does not work or is very low.

People who have a normal gene and a gene with biotinidase deficiency have 50% levels of enzyme activity but are sufficient to prevent symptoms. These people are called carriers (heterozygotes) of biotinidase deficiency.

All parents of a child with biotinidase deficiency are carriers that have generated a recessive condition. This gene is not identified except when the father and mother are carriers and generate a recessive child. The probability of carrier parents generating a carrier child is 50% for each pregnancy. Already the chance of generating a child with biotinidase deficiency is 25% in each pregnancy. And there is also a 25 percent chance of generating a child who does not carry the "defective" gene.

That is, a couple may have more than one child with biotinidase deficiency. But at the same time you can simply have a child without even having the biotinidase deficient gene.

If you have a child with biotinidase deficiency, make sure your other children (if any) have taken the biotinidase deficiency test. Everybody should do it.

Biotin or Vitamin B7

• Best Naturals Maximum Potency Biotin 10,000 Mcg for Healthier and Longer Hair Growth Support Formula, 200 Count

Biotin or Vitamin B7

Biotin, which can also be called vitamin B7, is an important vitamin that integrates the B complex. Because it is soluble in water, the body can not store it and needs its constant production and ingestion.

Benefits of Biotin

Its benefits are several, since it helps the body to convert nutrients into energy, and one of the best known is to maintain the health of hair, nails and skin . In the past, it has been named "Coenzyme R" and "Vitamin H", which comes from the German "Haar" (Hairs) and "Haut" (Pele).



Best Naturals Maximum Potency Biotin 10,000 Mcg for Healthier and Longer Hair Growth Support Formula, 200 Count

Biotin: What It Is for

Biotin serves to improve the metabolism of macronutrients in digestion, as it is part of the functioning of various enzymes in the body, known as the carboxylases. Such enzymes activate the production, for example, of fatty acids and glucose (gluconeogenesis), from the breakdown of important amino acids, such as leucine.

Thus, biotin is involved primarily in energy production , participating in the metabolism of carbohydrates, fats and proteins that we eat, which are broken down into nutrients of smaller units and finally can be absorbed by the body.

In addition, the benefits of vitamin B7 benefit the heart and circulatory system because it helps to reduce triglycerides, which are harmful elements in the circulation, and consequently reduces "bad" cholesterol and increases "good" (HDL) cholesterol: which means lessening the risk of hypertension and arteriosclerosis.

Biotin is considered important in the production of myelin, which is a protective covering of nerve fibers in the eyes, brain and spinal cord. Those who have Multiple Sclerosis (MS), an autoimmune disease, have a progressive destruction in the myelin, so biotin can help to regenerate this tissue.

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There are already researches that prove that high doses of biotin produce clinical improvement in patients with Multiple Sclerosis . Bone marrow and other nerve cells can grow or be repaired with biotin.

The gain of muscle mass is similarly provided by biotin, especially when there is damage to the muscles and these need repair - after long training in muscle hypertrophy, for example. Biotin-containing enzymes perform protein synthesis , which is required for muscle growth.

Regulate Glucose

Another benefit of biotin is in regulating sugar levels - glucose - in the body. With its stability, when there is a good functioning of enzymes, biotin prevents the glucose from suffering shortage or excess, balancing insulin levels and insulin sensitivity. This is how Type 2 Diabetes is prevented. But for this, a minimally balanced diet is also needed, without sugar exaggerations.

To demonstrate such a benefit, some controlled studies in diabetics have indicated that biotin supplements in conjunction with mineral chromium may help treat some people with Type 2 Diabetes, as compared to healthy subjects, patients with Type 2 Diabetes may have lack of biotin in the body.

Biotin in Pregnancy and Breastfeeding

During gestation and breast-feeding , biotin is also a very important component as there is an increased need for vitamin B7. It is estimated that up to half of pregnant women may have a mild biotin deficiency, but this does not always produce noticeable symptoms.

The hypothesis is that this deficiency occurs because of the faster metabolism of biotin in the body during gestation. And this may still interfere with the development of the fetus, so many pregnant women receive supplementation of Complex B by the doctor. And finally, one of the first known benefits of biotin is still the strengthening of the nails and hair.

Biotin for Hair and Nails

The brittle nails are those that easily crack, peel or chip. The estimate is that this condition affects about 20% of the world's population, not necessarily for lack of biotin, but often the vitamin helps to reverse the situation.

Some studies have already been done in which at least 25% of participants with fragile nails who received biotin supplementation had improvement after at least 5 weeks of treatment. In the case of hair, the mechanism is the same: deficiency of vitamin B7 can lead to hair loss, although there are few studies on this.

Biotin Deficiency

Biotin deficiency can still affect the health of the skin, causing seborrheic dermatitis and symptoms such as redness and scaly rash , which can be reversed with a good diet with biotin. The hypothesis is that this benefit to the skin, nails and hair is related to the breakdown of fat provided by biotin, but there is still no scientific evidence.

Sources and Biotin Supplement

Biotin is found in many foods, so it is difficult to need supplementation of vitamin B7, the manipulated biotin. But it may be indicated to improve the health of certain at-risk groups, such as pregnant women, athletes, and the elderly.

There are also rarer cases of hereditary biotin disease, in which biotin supplementation is extremely necessary. The best biotin supplement is for oral use , as ointments and gel for skin and hair usually do not work.

Main Foods

Probiotic bacteria in the gut are capable of producing biotin, and we can also find it in various foods . The main sources of biotin are:

•     Fish
•     Bull's liver
•     Egg yolk
•     milk
•     Whole Rice
•     Potatoes

Still found in other foods like: soy, oats, nuts, spinach, broccoli, cauliflower and bananas.

Important: Egg white should always be cooked or fried to deactivate avidin protein, which prevents the absorption of biotin.

Recommended daily intake

The recommended biotin intake per day is 5 mcg for children and 30 mcg for adults . For pregnant or lactating women, this amount may increase to 35 mcg per day .

Biotin deficiency is not very common because bacteria and food usually have enough of the body's needs. And as for weight, biotin does not fatten or supplement. Since it is a vitamin, it has no calories. Biotin may even aid in weight loss if accompanied by a balanced diet.