BioOptimal Collagen Powder, Collagen Peptides Grass Fed, Non-GMO Premium Quality Hydrolyzed Collagen Protein, Pasture Raised, Dissolves Easily, 300 Grams

BioOptimal Collagen Powder, Collagen Peptides Grass Fed, Non-GMO Premium Quality Hydrolyzed Collagen Protein, Pasture Raised, Dissolves Easily, 300 Grams

What are collagen peptides?

Collagen peptides - THE EXPERTS in health and beauty

Collagen peptides are a versatile source of protein and an important element of healthy nutrition. Its nutritional and physiological properties promote the health of bones and joints, and contribute to beautiful skin.

Collagen is composed of three polypeptide chains. These so-called alpha-chains are intertwined with each other to form triple-helical macromolecules. They have a sequence of amino acids, of unique size and exclusive structure. In the collagen sequences, glycine (Gly) is present as a tertiary residue. This allows the formation of the three chains in a triple helix structure. Therefore, the common feature for all collagens is a sequence that can be expressed as (Gly-XY) * n, where X and Y are frequently represented by proline (Pro) and hydroxyproline (Hyp), respectively. It is necessary so that the collagen can be mounted on fibrils. These, in turn, form fibers that give the extracellular matrix of the connective tissues their unique structure and strength.

The raw material used to obtain the collagen peptides, as well as for gelatin, is the collagen protein. The collagen peptides, however, are relatively small molecules with molecular weight less than 10,000 g / mol. The peptides are composed of at least 2 and at most 100 amino acids. They are characterized by an excellent solubility in cold water and do not form gels even in highly concentrated solutions.


BioOptimal Collagen Powder, Collagen Peptides Grass Fed, Non-GMO Premium Quality Hydrolyzed Collagen Protein, Pasture Raised, Dissolves Easily, 300 Grams

Great Lakes Gelatin, Certified Paleo Friendly, Pasture-Raised Grass-Fed, Collagen Hydrolysate, Collagen Peptides, Non GMO, 16 oz, 2-Pack, Frustration Free Packaging

Great Lakes Gelatin, Certified Paleo Friendly, Pasture-Raised Grass-Fed, Collagen Hydrolysate, Collagen Peptides, Non GMO, 16 oz, 2-Pack, Frustration Free Packaging

What is the benefit of hydrolysed collagen?

Benefits of hydrolysed collagen taken orally

It is interesting to know how collagen acts when taken orally, provided it is the appropriate form of collagen.

Collagen is a very abundant and widespread protein in the body and provides structure, resistance and elasticity to all tissues of the osteoarticular system and to the skin.

From the age of 25-30 years, the cells that synthesize collagen slow down their capacity for synthesis, which has important effects on our body.

Collagen is the glue that holds our body together, and that accounts for 76% of the connective tissue, skin and muscles.

Being an essential constituent of bones, cartilages, tendons, ligaments and joints.

The loss of collagen is the main cause of wrinkles, flaccidity and other torments of age.

When the loss of collagen occurs at the level of articulation, the cartilage loses thickness and resistance, degrades and the bones begin to rub against each other causing pain of osteoarthritis.



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When the loss is at the bone level, the bone becomes porous and brittle due to decalcification, since the calcium salts that are attached to the collagen are also lost.

This leads us to think that the calcium taken orally either in supplement or in the diet is not absorbed or used without the presence of collagen.

When it affects the skin, it loses thickness and elasticity, causing flaccidity and wrinkles.

All these processes are accelerated with the arrival of menopause due to the decrease in hormone levels.

The collagen in the food has a very low bioavailability, which must be supplemented to get a sufficient contribution to the body.

HYDROLYZED COLLAGEN

Collagen is a protein difficult to digest, it is practically not assimilable less than 1%, but when it is subjected to enzymatic hydrolysis, in which the polypeptide chains of the strand are fragmented, which are reduced to peptides and amino acids (AA) with a average molecular weight of around 4000 Da giving rise to CH hydrolyzable collagen, it becomes more digestible (absorption greater than 80%) why its molecular weight is much smaller and will be able to cross the intestinal barrier and via blood reach the collagenous tissues to nourish them.

Upon reaching the collagenous tissues, the hydrolyzed collagen stimulates the work of the cells of our body responsible for synthesizing collagen, (chondrocytes in the cartilages, osteoblasts in bones and fibroblasts in skin and connective tissue)

At a cellular level, scientific studies have shown that the presence of hydrolyzed collagen stimulates the synthesis of collagen itself, therefore tissue is regenerated.

The effect of collagen is dose-dependent, that is, it does not effect at low doses. The intake of 10 grams of collagen per day is recommended, a minimum concentration of collagen peptides is needed to stimulate the regenerative process and a minimum amount of CH ingested to receive health benefits within a reasonable period of time (3 months for reduction of joint pain of wear)

No results have been obtained with non-hydrolyzed collagen or with hydrolyzed proteins other than collagen.

Said dose in capsules would imply at least 10-15 capsules a day which would inconvenience the consumer, that is why it is in powder form.

Dermal studies have shown that taking 10 g of hydrolyzed collagen daily reduces the depth of skin wrinkles.

It has no side effects and contraindications except those people with severe kidney or liver problems and who must follow a low protein diet.

It is a supplement that can be consumed for a long period of time. Rest periods are recommended after three months of treatment of at least one month.

The benefits are noticed after 15 days and if you stop taking the effect it disappears.

It is a product free of fat and with a very low caloric intake of carbohydrates, so the caloric intake is not very high.

In case of people who have a diet with high protein intake, they should temporarily restrict the single protein intake.

They can consume gluten intolerant or lactose intolerant.

Poly-medicated people are better advised to consult with their doctor because although they should not present incompatibilities with the consumption of medications, any product can alter the absorption of medications.

Taking Hydrolyzed Collagen is no problem in healthy people that leads a balanced life, but in case of any doubt related to health issues, it is recommended to consult.



Thus, collagen contributes to the natural regeneration of tissues, especially cartilage, tendons and bones.

It contributes to improving the mobility of the joints and keeps them in perfect health.

Prevents injuries of athletes, such as tendonitis and strains and promotes recovery.

It helps reduce pain in people of advanced age and those who exercise.

Improves the appearance of the skin, nails and hair.

Composition of amino acids:

Glycine, Proline, Alanine, Hydroxyproline, Glutamine, Arginine, Aspartic Acid, Serine, Lysine, Leucine, Valine, Threonine, Phenylalanine, Isoleucine, Hydroxylysine, Histidine, Methionine, Tyrosine.

WE RECOMMEND:

I have tried both and they have gone very well, the only difference is that the Colnatur I do not like the taste and add honey.

COLNATUR:

Natural assimilable collagen, neutral taste.

How to use: take 10 g daily dissolved in animal or vegetable milk, yogurts, infusions.

300 gr pot

Prepared by: Protein

COLLAGEN + HIALURONIC EPAPLUS:

High solubility, low caloric intake and does not cause allergies.

Hyaluronic acid has been added to this formula to keep synovial fluid in the joints more elastic and viscous.

The hyaluronic contribution allows recovering the viscosity and elasticity as well as the flexibility and lubrication of the joints. It favors the conservation of the cartilage

420 gr pot price approx. € 21.00

Recommended daily amount: 14 gr a scoop and ½ in a glass of water juice or coffee, preferably in the morning, tastes like vanilla.

It has vanilla flavor, for the hyaluronic it costs a little to undo.

Pharmaceutical Peroxides Laboratory.

Some people have hyaluronic stomach discomfort.

COLLAGEN WITH MAGNESIUM OF ANA Mª LAJUSTICIA powder of 350 grs

DR Lajusticia adds magnesium to its formula, since magnesium is a catalyst in almost all the chemical reactions that are generated in our body, contributing to the good functioning of the muscles.

If you are interested in the subject I recommend a book, which explains very well the consequences of the lack of collagen.

Win the Osteoporosis of Ana Maria Lajustica ed Edaf

We have introduced Prisma Natural's collagen into our pharmacy because they are more specific compounds for different problems.

• Collagen Plus Daily
• Collagen Plus Flexyplus
• Colageno Plus Soprt
• Collagen Plus Woman

Orgain Grass Fed Hydrolyzed Collagen Peptides Protein Powder - Paleo & Keto Friendly, Amino Acid Supplement, Pasture Raised, Gluten Free, Dairy Free, Soy Free, Non-GMO, Type I and III, 1 Pound

Orgain Grass Fed Hydrolyzed Collagen Peptides Protein Powder - Paleo & Keto Friendly, Amino Acid Supplement, Pasture Raised, Gluten Free, Dairy Free, Soy Free, Non-GMO, Type I and III, 1 Pound

What are the amino acids of collagen?

INTRODUCTION

A protein is defined as collagen if it contains the triple collagen helix predominantly in its molecular structure forming an extracellular aggregate with a predominantly structural function.

Collagen is an insoluble fibrous protein that is characterized by containing large amounts of a regular structure forming a cylinder of great length. Collagen is found in all tissues in which it serves as a support frame. Its importance corresponds to its high percentage: for example, it means 4% of the liver, 10% of the lungs, 50% of the cartilage and 70% of the skin.

Collagen is composed of three chains that form a triple helix ( * ) Each chain has about 1400 amino acids of which one in three is a glycine. At other regular intervals, there are other amino acids, proline and hydroxyproline, which are rare in other proteins. The presence of these particular amino acids allows the three chains to coil around each other forming a very resistant fiber. In addition, hydrogen bonds are established between the chains, which give the collagen great stability.



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At least 12 types of collagen are known, numbered I to XII ( * ). The simplest, type I contains a long strand of triple helix that ends in the so-called telopeptides (each of which ends in a -COOH or -NH2 terminal), which are small segments that no longer have superhelical structure. Type I collagen molecules are associated side by side with a reaction catalyzed by a specific enzyme, the lysyl oxidase which binds the hydroxyproline of one chain with a lysine residue of another chain. In this way, long fibers are formed. In other types of collagen, the chains end up with more or less globular structures. For example, the basement membrane that supports the skin is a type IV collagen ( * ) that has a globular end or head and an extra tail. In the basal membrane, the heads are joined to one another while the tails are associated four to four forming complexes in the form of X. In this way a reticulum is formed in which other molecules (in this case laminin and other proteoglycans) ) intersect forming a dense sheet ( * ). Type I collagen is encoded by the COL1A1 and COL1A2 genes .

Type II collagen ( * ), abundant in the hyaline cartilage, in the vitreous of the eye and in the nucleus pulposus of the intervertebral discs, is made up of much thicker fibers.

Collagen type III is encoded by COL1A3 . It is found in almost all tissues in which type I appears as exceptions, bones, tendons and cornea.

Type VI collagen ( * ) is found in many tissues, including the aorta, tendons and skin. It is produced by fibroblasts.

The synthesis of collagen begins in the cytoplasm, forming isolated chains that are taken to the endoplasmic reticulum where the lysine and proline residues are hydroxylated, by means of enzymes that require Fe + 3 and vitamin C as cofactors ( * ). The hydroxylation of proline makes the protein thermostable, while the hydroxylation of lysine will allow the crosslinking of several triple helices. At this point, the glycosyl transferases of the endoplasmic reticulum glycosylate some hydroxylysine residues. The triple helix is ​​then assembled with the ends remaining as free polypeptides, which can be folded to form the globular structures. The triple helices are transported to the Golgi apparatus where they are modified by sulphation, some serines being phosphorylated. The resulting resulting procollagen is excreted from the cell through secretory vesicles.

The conversion of procollagen to collagen takes place extracellularly. The terminal telopeptides are hydrolyzed by specific proteases and the triple helices are assembled into fibrils, at which time other connective tissue proteins such as laminin can participate. Some of the hydroxylysine residues are converted to reactive aldehydes by lysyl oxidase, aldehydes that react with other lysine or hydroxylysine residues to form the crosslinks.

COLLAGEN DISEASES

Some details are known of the defects that can occur in the synthesis of collagen and associated diseases:

•     Ehlers-Danlos syndrome: this name is given by a set of at least 10 disorders that are clinically, genetically and biochemically different, but all of them are manifested by a structural weakness of the connective tissue.
•     Osteogenesis imperfecta: at least 4 diseases with this name characterized by multiple fractures and deformities are known
•     Scurvy: results from the deficiency of vitamin C in the diet, which can not form hydroxyproline because the enzyme lysyl oxidase needs this vitamin as a cofactor. Collagen in patients with scrobute is less stable than normal, which explains many of the clinical manifestations of this disease
•     Marfan syndrome: a connective tissue disorder that affects mainly the musculoskeletal and cardiovascular systems and the eyes. The patients show an asthenic complexion, with tall stature, long arms and hands and fingers like those of a spider. The musculature is poorly developed, with little subcutaneous fat and great laxity of the joints and ligaments. The disease is due to a mutation of the FBN1 gene that encodes fibrillin-1

Cutis lax    

    Cutis lax: a very rare disease, acquired or congenital, in which the degeneration of the elastic fibers of the skin makes it loose and pendulous. The disease is due to a defect of lysyl oxidase, a copper-dependent enzyme that catalyzes the cross-linking reactions of elastin


Kuivaniemi et al. (1997) have reviewed data on the nearly 278 different mutations found in the genes encoding type I, II, III, IX, X, and XI collagens of 317 unrelated patients. Most of the mutations (217, 78% of the total) were from a single base, either by exchange of a codon of a critical amino acid or by an abnormal splicing of the RNA.

Mutations of these 6 collagens cause a wide spectrum of diseases of bone, cartilage, and blood vessels, including osteogenesis imperfecta, a wide variety of chondrodysplasias, Ehlers-Danlos syndrome types IV and VII, and, occasionally, rare types of osteoporosis, osteoarthritis. and family aneurysm.


Collagen is used in cosmetic surgery in the so-called collagen replacement therapy, a procedure that involves injecting subcutaneously natural or synthetic collagen in the areas where wrinkles ( * ), scars or other imperfections of the skin are to disappear.

They are also being used as support in cultures of cartilaginous cells to subsequently implant patients who have suffered injuries, with a new technology called tissue engineering.

Youtheory Collagen Advanced with Vitamin C, 290 Count (1 Bottle)

Youtheory Collagen Advanced with Vitamin C, 290 Count (1 Bottle)

How is collagen synthesized?

Collagen synthesis

Previous sections have anticipated the autonomous ability of the human body to synthesize its own collagen and how that capacity is suffering a slow and irreversible deterioration with the passage of time, to the point of becoming half of the original at the approximate age 30 years old

Likewise, it has been apostilled about certain situations that accentuate this deterioration, being the most relevant the one that happens with the arrival of the climacteric in the female sex, something that is explained by the strong dependence of the intervention of the estrogens that characterizes the synthesis of collagen .

If we propose to select a truly key factor in accentuating this deceleration in the ability to synthesize collagen, perhaps we should point to what is known as " oxidative stress " derived from the accumulation of free radicals in cellular metabolism, among whose causes, to its Psychological stress, environmental pollution, excessive exposure to sunlight, a deficit of restful sleep, or the intake of medicines and stimulants , all of which can be enhanced with a diet lacking in vitamins, minerals and sources natural collagen (which will be discussed in detail in later sections).



Youtheory Collagen Advanced with Vitamin C, 290 Count (1 Bottle)

oxidative stress
Avoid degradation of collagen synthesis

In this order of things, we must bear in mind that the available weapons to stop the degradation of collagen synthesis point to two complementary fronts: on the one hand, to reduce oxidative stress and, on the other, to try to ingest the greatest amount of nutrients that contain principles favoring the synthesis of this capital protein structure. It is evident the advisability of eating a diet rich in collagen precursor foods, such as those that will be pointed out later, a diet in which the consumption of those foods that produce, albeit transiently, hyperglycemia, should be postponed, since This is the so-called glycation, a process by which surplus sugar molecules adhere to the collagen fibers to the detriment of their strength and flexibility.
Collagen synthesis


Let's go on to describe in detail how the synthesis of collagen develops in the bowels of the organism. This has its beginning in the cellular cytosol , where chains of isolated amino acids are made that are transported to the rough endoplasmic reticulum, that ribosome rich organelle where the remains of lysine and proline undergo the necessary hydroxylation to transform into the two main amino acids, together with glycine, from the collagen molecule: hydroxyproline and hydroxylysine. For this chemical reaction to take place it is essential that there is a sufficient amount of iron in its reduced form (+3) and vitamin C, both cofactors strictly necessary for two enzymes, prolyl-4-hydroxylase and lysyl-hydroxylase, trigger the reaction.
What is the importance of hydroxylation of both amino acids?

proline
Specifically, as far as proline is concerned, it is responsible for making collagen a more thermostable protein than most, while that of lysine is what makes the formation of the triple helical characteristics that collagen adopts as a structure high school.

After the hydroxylation arrives another determinant phase carried out by enzymes present in the endoplasmic reticulum, the glycosyl transferases , responsible for glycosylation, that is, to join a molecule of glucose, hydroxylysine residues so that this triple helical figure is perfectly assembled with the ends occupied by free polypeptides, which constitute the starting point of the classic folding in globular form that characterizes the quaternary structure of collagen.

Golgi apparatus Finally, the triple helices are transported to another prominent organelle of the cellular cytoplasm, the Golgi apparatus , in which they are subjected to a sulfation reaction involving the amino acid cysteine ​​rich in sulfur, to which is added the phosphorylation of its homolog serine.

At the end of these stages, the resulting metabolite is the procollagen or immature form of collagen, whose fate is its evacuation by the fibroblast to the intercellular matrix using its secretory vesicles. In this extracellular fluid, procollagen becomes the substrate of new enzymes, peptidases and proteases, which give rise to the tropocollagen molecule, the stage immediately prior to the definitive collagen fiber. The dimensions of the tropocollagen are 300 nanometers in length and 1.4 in diameter and are formed by three polypeptide chains, of about 100,000 daltons of molecular weight each, called non-helical α-chains, of levorotatory configuration and each of which is composed of a polypeptide containing a tandem replica of three amino acids.
Defects of collagen synthesis

In all described above can be given a series of Defects of collagen synthesis .

Collagen Peptides Protein Powder - Grass Fed, Pasture Raised with Aminos - Promotes Healthy Skin Hair & Nails – Bone & Joint Support - Hydrolyzed, Unflavored, Non GMO, Gluten Free - Easy to Mix -16 oz

Collagen Peptides Protein Powder - Grass Fed, Pasture Raised with Aminos - Promotes Healthy Skin Hair & Nails – Bone & Joint Support - Hydrolyzed, Unflavored, Non GMO, Gluten Free - Easy to Mix -16 oz

What are the types of collagen?

Discover the different types of collagen!

As we discussed in our previous post, collagen is the most abundant protein in our body . There are many types of collagen and each helps with a part of our body. We will focus on three types of collagen and discuss what forms can be found in most stores.

The collagen must come from natural sources and be obtained through a specific enzymatic hydrolysis process. This is the only way to ensure that all fragments are of the same size and composition, which ensures their complete absorption and assimilation.
Types of collagen

•     Type I: comprises 90% of the skin, hair, nails, organs, bones and ligaments. If you're looking for a collagen with anti-aging effect, this type of collagen is considered the best.
•     Type II: shapes the cartilages.
•     Type III: we find it in bones, cartilages, dentine, tendons and other connective tissues.

Collagen, vitamin C and hyaluronic acid

You can acquire collagen powder, pills or liquid collagen, but it is important that it contains vitamin C and hyaluronic acid. Minerals such as zinc, calcium, magnesium, vitamins such as D, K, B12, B6 or Coenzyme Q10, will help to make the action of collagen more complete.



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Vitamin C is key to the synthesis of collagen. Without it, taking collagen does not help much. Whether you take collagen powder, pills or liquid, make sure it contains vitamin C.

It has been confirmed that hyaluronic acid is an essential element to retain the internal hydration of the skin . According to studies, people who ingest hyaluronic acid for four weeks show more hydrated skin, a reduction in wrinkles and an overall improvement in their appearance.
Hydrolyzed collagen

It is a protein obtained through a hydrolysis process. Quite simply, what is achieved is to decrease the molecular weight of the collagen protein so that we can assimilate a greater amount of it.

It has a very low calorie value and does not contain sugar. It helps soften stretch marks but does not eliminate them completely. It also helps to improve flaccidity and, if combined with a daily walk of 30 minutes, will enhance the results. You will notice that hair and nails grow more vigorously and quickly.
Collagen powder, collagen in tablets or liquid collagen

The recommended daily dose of collagen is at least 10 grams per day. We can find this protein in capsules, powder or liquid.

Some people prefer to take collagen powder. You can take dissolved hydrolyzed collagen powder in a glass of freshly squeezed orange juice.
Collagen: against indications

In general, collagen is a safe substance although some recommendations can be made:

•     Collagen, being protein, is not indicated for low protein diets .
•     People with allergies to animal protein should not consume it, nor those who suffer from hereditary phenylketonuria or phenylalanine intolerance.
•     There brands can contain lactose, sugar or sucralose. If you are allergic to any of these substances you should look at the list of ingredients before ingesting collagen.
•     Some collagens of marine origin contain a lot of calcium. If you do not want to consume this mineral, you can opt for collagen of porcine origin.

Remember that the results of collagen in the body are visible after three months. The body assimilates collagen and works from within. Be patient and give your body the time it needs.

Premium Multi Collagen Peptide Capsules (Types I,II,III,V,X) - Anti-Aging Formula, Healthy Skin & Hair, Strong Joints, Bones & Nails - Hydrolyzed Protein Supplement for Women and Men - 30 Day Supply

Premium Multi Collagen Peptide Capsules (Types I,II,III,V,X) - Anti-Aging Formula, Healthy Skin & Hair, Strong Joints, Bones & Nails - Hydrolyzed Protein Supplement for Women and Men - 30 Day Supply

What amino acids make up collagen?

Introduction
Collagen is a fibrous protein that forms the connective tissue, and in mammals and birds it constitutes a very important proportion of total proteins, of the order of a quarter of the total, which makes it the majority.

There are several types of collagen, designated by Roman numerals. In type I collagen, the most abundant, the constituent structural unit is the tropocollagen, a protein of around 300,000 molecular weight, made up of three chains of the same size, two of them identical, called 1, and another slightly different, the a 2. The three chains are joined together by hydrogen bonds between the amino and carboxyl groups of the glycine residues, and by hydrogen bonds with the hydroxyproline side chains, forming a triple helix, peculiar structure of the Collagen This propeller only breaks at the ends.

Collagen type III is formed by three identical chains to 1, and has the peculiarity that at the carboxyl terminal end the three chains are not grouped in helical form, but joined together by disulfide bridges. This type of collagen, located in the perimyo and endomysium of the muscle, seems to be especially important in terms of conferring hardness on the meat.



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The tropocollagen units, which have a length of about 2,800 amstrongs, are grouped in parallel, joined together to form the collagen fibers. Within the fibers, the units are displaced approximately a quarter of their length with respect to the adjacent ones, and each unit is about 400 amstrongs from the next one.

The amino acid composition of collagen is quite particular. Glycine represents, in moles, approximately 1/3 of the amino acids present. They also contain very high amounts of proline, and of hydroxyproline (up to 10%), and it is one of the few proteins that contains hydroxylysine. The presence of hydroxyproline is often used as an analytical criterion to evaluate the amount of collagen (connective tissue) present in minced meat products.

Both hydroxylysine and hydroxyproline are produced after the synthesis of the polypeptide chain, by modification of the non-hydroxylated amino acids by specific enzymes.

The primary sequence of collagen chains is also very peculiar, since, except at the ends of the chain, glycine is distributed regularly, occupying the position of one in three minoacids.

The peculiarities of the collagen sequence make possible its peculiar secondary structure. The small size of the glycine allows three chains to cross each other, while the rigidity produced by the proline ring favors the angle of rotation they adopt.

As the age of the animal increases, collagen has a higher number of crosslinks by covalent bonds between the chains. These bridges are formed by the initial action of the enzyme lysine oxidase, which transforms aldehydes into lysine or hydroxylysine, aldehydes that can later be condensed by spontaneous chemical reactions with other groups.

The heating of the collagen produces its denaturation, whose first consequence is an enormous shortening of the fibers, shortening that occurs at a temperature characteristic for the collagen of each animal species. The triple helical structure is also destroyed. The temperature at which the collagen is denatured depends on the content of proline and hydroxyproline: The higher the content, the higher the temperature required. In this sense, there is a great difference in proline content and in the temperature of denaturation between the collagen of warm-blooded animals and that of fish, both much smaller in the latter. In some cold-water fish, the collagen is denatured at less than 20 ° C. In cooking foods, part of the collagen is solubilized and forms the "gelatin", which imparts viscosity to the stews.

Collagen is an abundant component in skin, tendons, vascular system and other waste materials, from which commercial gelatin can be obtained, which is a product of partial degradation of collagen, extracted by heating after treatment in an acidic or alkaline medium. Depending on the type of treatment, a different type of gelatin is obtained. Gelatine is a very useful material in food technology, to obtain thermally reversible gels, with a very low "fusion" point. These gels are formed by cooling by the binding of chains by partial reconstruction of helices of the collagen type, but with large disorganized zones.

From a nutritional point of view, collagen and even gelatin are very unbalanced proteins in terms of their amino acid composition. Collagen is very deficient in tryptophan, and gelatine practically lacks it, since the little that existed is usually destroyed in its preparation. The ease with which it protects itself depends a lot on its state. Native collagen is quite resistant to proteoliis by most proteinases, while denatured collagen is easily hydrolyzed.

NeoCell Super Collagen and Vitamin C 6,000milligram Collagen Types 1 and 3 Plus Vitamin C,250 Tablets

NeoCell Super Collagen and Vitamin C 6,000milligram Collagen Types 1 and 3 Plus Vitamin C,250 Tablets

Demonstrate the efficacy of native type II collagen in the treatment of osteoarthritis

Native collagen type II reduces pain and inflammation and improves joint mobility in osteoarthritis, according to two studies presented by Bioibérica at the World Congress of Osteoporosis, osteoarthritis and musculoskeletal diseases (ESCEO 2015) held recently in Milan (Italy).

Native type II collagen is the main protein in the articular cartilage structure and provides resistance and strength. In general, in the joint pathologies degradation of this protein occurs, which leads to a degradation of the joints.



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Therefore, the oral administration of native type II collagen has been shown to help regulate the inflammatory response at the joint level, thus preserving the health of the joints.

The first of the studies was carried out jointly with the Department of Pharmacology of the University of Florence (Italy). It is a pre-clinical study with rats to which osteoarthritis was induced. The results show that a dose of only 10mg / Kg per day of native type II collagen improves pain and motor skills and decreases inflammation and joint degeneration.

In addition, it has been seen that its analgesic effect is comparable to that of the group to which 250 mg / kg of glucosamine was administered per day. "The demonstrated efficacy is especially relevant considering the dose to which native collagen is applied," says Daniel Martínez, director of R & D in the area of ​​Human Health of Bioiberica.

The second investigation is a clinical study done with the Faculty of Medicine of the Osmangazi University (Eskisehir, Turkey) with the aim of evaluating the effectiveness of this complement in the treatment of osteoarthritis of the knee. The patients were divided into two groups: one who took acetaminophen and another who took acetaminophen combined with native type II collagen for three months.

At the end of the study, patients treated with the combination showed a significant improvement in pain and mobility, compared to the start of treatment and in the group that only took acetaminophen. "The results show that native type II collagen can provide an additional benefit to conventional therapy," adds Martinez.

Ancient Nutrition Multi Collagen Protein Powder, 5 Types of Food Sourced Collagen, Providing Types I, II, III, V, and X, 16.2oz

Ancient Nutrition Multi Collagen Protein Powder, 5 Types of Food Sourced Collagen, Providing Types I, II, III, V, and X, 16.2oz

The 6 benefits of collagen for the elderly

The lack of collagen in our body has many consequences for the elderly : the appearance of diseases of bone fragility such as osteoporosis, joint pain, the appearance of wrinkles, hair loss ... Taking hydrolyzed natural collagen can help prevent or reduce those consequences . In this article we analyze its benefits.

Over the years, our body generates less amount of collagen. Collagen is an essential protein. It is the most abundant in our body. It gives elasticity, resistance and flexibility to the body's tissues. It is key in the strength of bones, in the health of tendons, ligaments and joints or in the vitality of our skin.

Taking natural collagen has 6 benefits for the elderly . They are the following:



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1. Helps prevent the onset of osteoporosis and bone fragility

Calcium is responsible for keeping our bones strong. But if we lack collagen, the body does not have the capacity to take advantage of it. The bones are formed from a collagen mesh. The collagen protein is responsible for fixing calcium in the bone. To have hard and strong bones, we need to have adequate levels of collagen in that mesh.

Taking collagen helps prevent the onset of diseases related to bone fragility such as osteoporosis . Also, if you already have that disease, it can help reduce your symptoms.
2. Reduces joint pain

The daily intake of collagen can reduce pain, inflammation, edema and stiffness of rheumatoid arthritis, osteoarthritis, juvenile arthritis and gout . Taking collagen helps repair all the cartilaginous tissues of our body. Among them, those of the joints: knees, joints of the fingers, elbow, neck, etc.

The wear of the articular cartilage causes chronic pain and the loss of the mechanical capacity of the tendons and ligaments, contributing to the inactivity of the joint and aggravating the problem. Scientific studies show that ingesting a quality supplement such as Colvitae strengthens the joints and prevents or reduces pain.
3. It improves the health of the skin and reduces wrinkles

The collagen protein also acts on the tissues of the skin , favoring the reduction of wrinkles. Collagen helps to improve the general appearance of the skin, helps regenerate the connective tissues of the skin and stimulates the formation of natural collagen to preserve a soft, supple, young and more resistant skin.

With the passage of time the dermal collagen is reduced. The union between the skin cells decreases. The consequence is the loss of firmness and elasticity. The skin ages and wrinkles appear.

Taking natural collagen helps maintain the flexibility, strength and firmness of the skin. When wrinkles already exist, it helps to reduce them.
4. Help strengthen hair

Collagen also has a key role in the strength and vitality of hair. Taking natural collagen helps maintain a strong and healthy hair; avoiding its loss.
5. Helps strengthen the nails

Another part of our body in which collagen is essential are nails. Like the bones, the nails are formed by a collagenous mesh that holds the cells. Strength depends on the health of that mesh.
6. Vitality!

Reduce the symptoms of bone fragility or osteoporosis, reduce joint pain, decrease wrinkles and improve the health of our skin, strengthen hair and nails ... all this leads to feel better and, consequently, feel more vital. Collagen can help you recover that vitality you had lost to continue enjoying life and yours.

Taking hydrolyzed nautral collagen is recommended in older people to enjoy better health and quality of life.

NeoCell Super Collagen Powder 6,600milligram Collagen Types 1 and 3 Unflavored 7 Ounces

NeoCell Super Collagen Powder 6,600milligram Collagen Types 1 and 3 Unflavored 7 Ounces

Collagen, Elastin and Hyaluronic Acid: the 'must have' for your skin

Hello beautiful! As you know, hydration and firmness are the two necessary pillars for a beautiful and young skin. As active as collagen, elastin or hyaluronic acid, are the bases of the formula to achieve this goal. Today we tell you everything about them:

- Collagen: is, so that we understand the "glue" of the body. An essential protein that is present throughout our body (30% of our body is composed of this substance), muscles, tendons, bones and skin. Its cutaneous function is to give the skin strength and structure, as well as being its internal support . It is responsible for keeping the skin firm and elastic. The bad news is that, over the years, not only do we generate less collagen, but also, it is of poorer quality: weaker, more disorganized ... And for that reason, the feared flaccidity appears.

- Elastin: elastin also has structural functions although, unlike collagen, it gives more elasticity than resistance. Elastin is part of the connective tissue of the skin forming fibers (similar to an elastic net) and keeps the skin firm and looking good . Although it is not as abundant as collagen, elastin plays a key role in keeping our skin young. However, as with collagen, the passage of time reduces its production and quality.



NeoCell Super Collagen Powder 6,600milligram Collagen Types 1 and 3 Unflavored 7 Ounces

- Hyaluronic acid: hyaluronic acid is a substance found mainly in the skin, but also in joints and cartilage. Over time, they are destroyed and it is estimated that when we reach 50 years, we only have half of hyaluronic acid in our body. For this reason, many cosmetics use it, since the replacement of this component in the skin is necessary to keep it nourished. Its main feature is that it is able to retain water in more than a thousand times its weight, to deposit it in the epidermis (thus, it captures moisture in the environment to give it to the skin and also prevents the deeper layers of the skin dehydrate).

- The Deep Action Collagen and Elastin ampoule: an authentic cocktail of anti-wrinkle and rejuvenating active ingredients that will improve the elasticity of cutaneous fibers and compensate for the loss of both proteins caused by the passage of time.

- The Deep Action Ampoule of Hyaluronic Acid: it contains a very high concentration of this active, to compensate that, with age, it is destroyed.

Germinal is a brand created by Alter Laboratories that, in its almost 40 years of history, continues to maintain its initial vocation to make beauty more vivid and lasting, with high-cosmetic products sold in Pharmacy that, at the time of its creation, They did not exist. Throughout its history, Germinal has been developing products for women seeking specific treatments for their skin and in 2015 launches its preparations in ampules of Deep Action, destined to nourish the skin in depth and recover the firmness of it.

Great Lakes Gelatin - Collagen Hydrolysate Kosher - Unflavored Protein - 16 oz

Great Lakes Gelatin - Collagen Hydrolysate Kosher - Unflavored Protein - 16 oz

What is skin collagen?

THE POWER OF THE COLLAGEN

Collagen is a fundamental ingredient to provide smoothness and firmness to the skin.

One of the main concerns of women in terms of beauty is to maintain a youthful appearance. With age, wrinkles, lines of expression and spots appear, influencing the skin aging of our face. The dermatological and cosmetic treatments based on collagen are essential to combat the inexorable process of aging and delay its effects on the skin.

The range of collagen anti-aging care is used to achieve immediate and lasting effects to rejuvenate the skin, providing hydration and strengthening the tissues.

Collagen helps minimize the effects that gestures produce on the face. Its exceptional moisturizing action softens and smoothes the skin very effectively with amazing results. Of course, you have to be consistent in its use and try to use a product indicated to your skin type: fat, dry, mixed or sensitive.



Great Lakes Gelatin - Collagen Hydrolysate Kosher - Unflavored Protein - 16 oz

The collagen will act as a "mattress" on the fibers of the dermis and recover the skin, providing a unique volume and elasticity. Remember that to maintain a skin care and firm is not enough to apply collagen products, but also must be complemented with proper daily care. Do not forget to follow a few basic steps of daily routine that will keep your face always radiant and luminous:

EXFOLIATE. Use an exfoliating gel or mask to remove dead cells and impurities.

CLEAN AND TONIFY. Always remove your face with the help of a cleansing cream and then a facial tonic. Help yourself with a small cotton, so that the product penetrates more easily and you can remove the excess.

HYDRATE. Apply every day a moisturizer with sunscreen (even if winter) indicated for your skin type.

NOURISH. The use of a nutritive or regenerating cream will provide the nutrients that our skin needs. Ideally, apply it every night, before going to sleep.

Take care of your skin and keep a healthy and balanced diet, drink lots of water and do sport whenever you can. Help yourself with collagen to firm your complexion and blur the small wrinkles and lines of expression caused by age. Apply the product correctly, filling in the most visible areas, and repeat the same operation daily. Be persistent!

At present, there are also treatments with collagen that you can apply in specialized beauty centers and that will show results from the first session.

In short, use collagen to feel your skin firmer and smoother. It is a magic protein, the secret to keep skin young for longer.

Vital Proteins Collagen Peptides - Pasture Raised, Grass Fed, Paleo Friendly, Gluten Free, Single Ingredient (10 oz)

Vital Proteins Collagen Peptides - Pasture Raised, Grass Fed, Paleo Friendly, Gluten Free, Single Ingredient (10 oz)

What are foods rich in collagen?

Which foods contain more collagen

oods with more collagen are of animal origin , since it is an element that does not appear in fruits or vegetables. If we want a good contribution of collagen, the best we can do is pay attention to the following products:

•     Pig handyman
•     Cow nose.
•     Callos and varied casquería.
•     Bone broth, both meat and fish.
•     Gelatins made from animal products.

One of the great problems of collagen is that so that we can absorb it properly has to be hydrolyzed, that is, it is precisely in those foods that often seem unattractive because of its high content of fat and gelatin. Shellfish and animal gelatin are very high sources of collagen .



Vital Proteins Collagen Peptides - Pasture Raised, Grass Fed, Paleo Friendly, Gluten Free, Single Ingredient (10 oz)

If these foods seem too heavy, the truth is that pig's trotters and cow's nose, to give two examples, are not easy to digest, we can choose to prepare broths from meat bones or fish bones . Keep in mind that we are talking about very long cooking, in which we manage to undo all possible collagen from these products.

Collagen, in any case, is not something that we should consume daily and is recommended, especially after a certain age, as long as we have some deficiency caused by arthritis, fractures or injuries . A healthy adult produces enough collagen by itself, as long as it maintains a normal diet, rich in vitamins and minerals.

There are a number of foods that help the natural production of collagen :

•     Fruits and vegetables rich in lycopene, such as apples, strawberries or beets.
•     Fruits rich in vitamin C.
•     Celery, cucumbers, garlic, onions and other products rich in sulfur.
•     Soy milk and cheese, thanks to its genistein content.