Demonstrate the efficacy of native type II collagen in the treatment of osteoarthritis
Native collagen type II reduces pain and inflammation and improves joint mobility in osteoarthritis, according to two studies presented by Bioibérica at the World Congress of Osteoporosis, osteoarthritis and musculoskeletal diseases (ESCEO 2015) held recently in Milan (Italy).
Native type II collagen is the main protein in the articular cartilage structure and provides resistance and strength. In general, in the joint pathologies degradation of this protein occurs, which leads to a degradation of the joints.
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Therefore, the oral administration of native type II collagen has been shown to help regulate the inflammatory response at the joint level, thus preserving the health of the joints.
The first of the studies was carried out jointly with the Department of Pharmacology of the University of Florence (Italy). It is a pre-clinical study with rats to which osteoarthritis was induced. The results show that a dose of only 10mg / Kg per day of native type II collagen improves pain and motor skills and decreases inflammation and joint degeneration.
In addition, it has been seen that its analgesic effect is comparable to that of the group to which 250 mg / kg of glucosamine was administered per day. "The demonstrated efficacy is especially relevant considering the dose to which native collagen is applied," says Daniel Martínez, director of R & D in the area of Human Health of Bioiberica.
The second investigation is a clinical study done with the Faculty of Medicine of the Osmangazi University (Eskisehir, Turkey) with the aim of evaluating the effectiveness of this complement in the treatment of osteoarthritis of the knee. The patients were divided into two groups: one who took acetaminophen and another who took acetaminophen combined with native type II collagen for three months.
At the end of the study, patients treated with the combination showed a significant improvement in pain and mobility, compared to the start of treatment and in the group that only took acetaminophen. "The results show that native type II collagen can provide an additional benefit to conventional therapy," adds Martinez.