Starwest Botanicals Organic Turmeric Root Powder, 1 Pound Bulk
12 benefits of turmeric: against cancer, diabetes, thrombosis, inflammation and other diseases
Many people know about turmeric thanks to the Indian dish - curry. These are a variety of stewed vegetables, legumes and / or meat. A blend of spices that are used for these dishes are also called curries. This term originated from the Tamil language, and is translated as “sauce.” Curry contains: turmeric, coriander, cumin, fenugreek, cayenne pepper, fennel, ginger, cardamom, cloves, white pepper, black pepper, jamaican pepper, Chinese cinnamon, nutmeg and white mustard.
The benefits of turmeric are well studied. PubMed has published more than 12 thousand articles proving the advantage of turmeric. ( 1 )
This puts turmeric in the first place on the list of herbs and spices. It is followed by garlic, cinnamon, ginseng, ginger and milk thistle.
Curcuma (Curcuma longa) grows in India and the countries of Southeast Asia. The dried root of this plant is ground into a characteristic yellow powder. Ayurveda says: “turmeric is the only spice that can purify the blood.”
Several compounds known as curcuminoids have been found in turmeric. The active ingredient is curcumin , defined by the Mayo Clinic as “a product that can have a positive effect on health in addition to basic nutrition . ”
Turmeric has very few side effects, and those that exist are very rare and mild. Therefore, it is a powerful and safe tool. Imagine if you could say that about all the drugs.
12 benefits of turmeric
1. May slow down and prevent blood clots.
Clots of blood clots are formed in the process of platelet aggregation . In this case, the platelets are concentrated in one area where a clot forms. When a large clot breaks off, it can block the vessel and instant death will occur.
Laboratory animal studies have shown that curcumin significantly reduces cases of platelet aggregation and potentially reduces the risk of clot formation. ( 2 , 3 , 4 )
Curcumin changes the internal process known as eicosanoid biosynthesis . Eicosanoids consist of four different molecules that are involved in the natural process of inflammation. It has been suggested ( 5 ) that one of the reasons why curcumin has anti-coagulation properties is its effect on the biosynthesis of thromboxanes , one of the four eicosanoids. This mechanism is one of the causes of the anti-inflammatory effect of turmeric.
A study in 1986 showed that curcumin may be the preferred treatment for people prone to vascular thrombosis and who need anti-arthritis therapy. ( 6 )
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2. Reduces depression
Numerous studies have been conducted proving the reduction of depression in animals as a result of taking curcumin. ( 7 , 8 , 9 , 10 )
These results appear to be related to how it affects the function of the neurotransmitter through the neurotrophic factor of the brain ( BDNF ). ( 11 )
In 2014, Phytotherapy Research published the amazing results of a study in which 60 volunteers diagnosed with depressive disorder took part. ( 12 ) Volunteers were divided into three groups: a group with curcumin, a group with fluoxetine, a combined group. Six weeks later, curcumin was found to be as effective as fluoxetine. The combination of curcumin with fluoxetine led to a slightly greater improvement, but the magnitude was statically insignificant.
After that, at least two other studies also observed the effects of curcumin on depressed patients. In the first, 56 people (men and women) participated, and in the second, 108 men. ( 13 , 14 ) Both used placebo, but did not compare curcumin with any antidepressant. Both studies have shown that curcumin effectively reduces the symptoms of depression, unlike placebo.
I found the perfect tea with a blend of spices called masala . These include black pepper, brown cardamom, green cardamom, nutmeg, turmeric, cumin and cinnamon . This drink helps me fight depression and depression. Preparing tea is simple: pour the milk into a saucepan or pan, throw two teaspoons of the mixture into 300 ml of milk and tea to taste (black or green). Bring to a boil, reduce heat and simmer for 3-5 minutes. Then strain and drink. I add ginger without fail. You can add sweetener to taste.
3. Fights inflammation
Curcumin is able to control inflammation. A study was published in the journal Oncogene , which evaluated several anti-inflammatory compounds and found that ibuprofen and aspirin (nonsteroidal anti-inflammatory drugs) are the least effective , unlike curcumin . ( 15 )
Diseases such as cancer, ulcerative colitis, arthritis, high cholesterol, fibromyalgia are associated with inflammatory processes.
The anti-inflammatory effects of curcumin have been studied as a possible treatment for Alzheimer's disease . According to the Alzheimer's Society, evidence of the effects of turmeric on Alzheimer's patients is inconclusive: there is no certainty that turmeric can prevent or cure this disease. ( 16 )
Several tests have been conducted to study the relationship between curcumin and Alzheimer's disease. In rats, curcumin appears to reverse the existing amyloid pathology and its associated neurotoxicity, which is a key sign of the progression of this neurological disease associated with chronic inflammation. ( 17 , 18 , 19 )
In human trials, no effect was recorded reflecting the results of animal studies. Researchers cite a small sample, limited research time, and the poor bioavailability of curcumin in the test samples as possible reasons for such results.
Today, scientists are still looking for the perfect curcumin formulation that will be bioavailable and that can penetrate the blood-brain barrier. But some time will pass before human tests confirm this specificity.
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4. Improves skin health
Anti-inflammatory and antioxidant properties of curcumin have proven to be effective in treating skin diseases. Benefits include: increased shine and radiance of the skin, accelerated wound healing, narrowing of pores, reduction of acne and acne scars, and control of psoriasis. ( 20 , 2 1 , 22 , 23 )
One uncontrolled pilot study involving 814 volunteers showed therapeutic effects of turmeric paste in 97% of scabies for 3-15 days. ( 24 )
5. Treats arthritis
A study was conducted in 45 patients with rheumatoid arthritis to compare the benefits of curcumin with diclofenac sodium , which puts people at risk for developing heart disease and gastrointestinal tract. ( 25 ) Patients were divided into three groups: a curcumin course, a diclofenac course, and their combination. The group with curcumin showed the greatest percentage of improvement in overall assessments and these indicators were significantly better than in patients in the group with diclofenac sodium. More importantly, treatment with curcumin was safe and had no side effects.
See also: Vitamin B12: what it is for, where it is contained, the deficit and the daily rate
A review of available RCTs confirmed that eight eligible studies proved the effectiveness of turmeric extract (about 1000 mg of curcumin per day) in the treatment of arthritis. ( 26 )
6. Can treat and prevent certain types of cancer.
According to world authorities such as Cancer Research UK : ( 27 )
“A number of laboratory tests for cancer cells have shown that curcumin has an anti-cancer effect. It seems that he is able to kill cancer cells and prevent their growth. It has the best effect on breast, intestinal, stomach and skin cancer. ”
A study conducted in July 2017 at the Baylor Scott & White Research Institute showed that curcumin can break through chemical resistance in adenocarcinoma of the pancreatic ducts - an aggressive form of pancreatic cancer. ( 28 )
Curcumin seems to re- sensitize the cancer cells of patients to drugs, although the exact mechanisms of chemo sensitization of curcumin remain ambiguous. The author of the study, Ajay Goel , director of the department of gastrointestinal research and translational genomics and oncology at the Research Institute Baylor Scott & White said : ( 29 )
"Food herbal remedies are able to restore more healthy gene expression in patients, but without the toxicity of some drugs"
This can help cancer patients with chemotherapy resistance.
7. Helps manage diabetes
In 2009, Biochemistry and Biophysical Research Communications published a laboratory study from Auburn University that explored the potential of curcuminoids for reducing glucose levels . ( 30 ) Research has shown that curcumin is 400 times more effective than metformin in the activation of the enzyme AMPK (AMP-activated protein kinase). One compound obtained by fermenting curcumin, tetrahydrocurcumin , activates AMPK 100,000 times stronger than metformin in certain cells.
Researchers believe that AMRK activation is a “therapeutic target” for type 2 diabetes. ( 31 ) And this means that figuring out how to activate this enzyme has great potential for developing more effective treatments for diabetes and insulin resistance.
Other mechanisms by which turmeric can effectively reduce or reverse diabetes symptoms are related to its anti-inflammatory effect. Multiple meta-analyzes have confirmed that curcumin significantly reduces inflammatory markers, including TNF-α and IL-6, which are associated with diabetes. ( 32 , 33 )
One of the most common complications of diabetes is nerve damage, known as diabetic neuropathy , which takes several forms and can have serious consequences, from muscle weakness to blindness . Studies in rats have shown that adding curcumin significantly reduces diabetic peripheral neuropathic pain, which is usually localized in the feet, legs, arms, hands. ( 34 )
This can lead to renal failure. A meta-analysis of RCTs confirmed that in animals with diabetes, curcumin protects the kidneys from damage and diabetic nephropathy .
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8. Fights obesity
A study published in the journal Biofactors found that curcumin can help reduce the growth of fat cells. Researchers have found that the anti-inflammatory properties of turmeric effectively suppress the inflammatory processes of obesity and help reduce it. ( 35 )
9. Helps to treat inflammatory bowel disease
A study was conducted in which people with ulcerative colitis took part. ( 36 ) Patients were divided into two groups. The first took curcumin along with mesalazine (nonsteroidal anti-inflammatory), and the second took placebo plus mesalazine. Patients from the placebo + mesalazine group were more than 4 times more likely to have relapses and exacerbations of ulcerative colitis during the six months of the study . This suggests that the benefits of turmeric may include helping to maintain remission of the disease.
One small pilot study examined the benefits of turmeric for patients with ulcerative colitis and Crohn's disease . ( 37 ) Although the sample size was small, all patients with ulcerative colitis and 4 of 5 patients with Crohn's disease showed an improvement within two months , which indicates the need for additional research.
Usually, patients with ulcerative colitis and Crohn's disease are prescribed corticosteroids , which reduce pain, but over time damage the intestinal mucosa, which causes a worsening of the condition. That is why these drugs can not be taken for a long time.
However, the addition of curcumin had no side effects in any of the above studies.
10. Can regulate cholesterol
The epidemic of prediabetes and diabetes is rampant. One of the main causes of death are cardiovascular diseases that have arisen against the background of these conditions.
People suffer from oxidative stress, which damages blood vessels. At the site of damage to blood vessels, the body begins to “ increase” cholesterol in order to “patch up” damaged areas, which leads to high levels of LDL. ( 38 )
Traditionally used drugs, statins , such as atorvastatin , are known to cause damage to the kidneys and liver and a number of deadly side effects . These drugs can lower cholesterol, but they do not eliminate the cause of high levels of LDL - oxidative stress caused by high blood sugar and systemic inflammation.
Western doctors are aware of the side effects of statins, and are increasingly prescribing curcumin and fish oil to patients.
A study ( 39 ) conducted by Drugs in R & D showed that curcumin is comparable to atorvastatin, but without side effects . This study was a continuation of a previous animal study that showed similar results. ( 40 )
However, a 2014 meta-analysis showed that curcumin did not have a general effect on cholesterol levels in the blood (together or divided into LDL and HDL) or triglyceride levels . The author of the analysis noted that these results may be related to the short duration of the study and the poor bioavailability of the studied curcumin formulations. ( 40 )
11. Has an analgesic effect.
In early 2014, the European Journal of Pharmacology published a study in which it was discovered that curcumin naturally activates the opioid system in diabetic rats. Other breakthrough studies and surveys (in animals and in humans) have shown that curcumin may be useful for:
wound healing ; ( 41 )
burn pain ; ( 42 )
postoperative pain ; ( 43 )
neuropathic pain caused by damage to the peripheral and / or central nerve; ( 44 )
arthritis pain ; ( 45 )
orofacial pain (associated with the jaw, face, and most often occurring against the background of dental problems); ( 46 )
pain in the sciatic nerve ; ( 47 )
joint pain . ( 48 )
See also: Selenium: what is it, what is it for, the daily rate, causes and signs of shortage, sources
A study in 2011 in animals showed that a high dose of curcumin relieves depressive behavioral problems in patients associated with pain . ( 49 )
12. Helps detoxify
An important advantage of turmeric is its ability to cleanse the body of toxins . Every day you are exposed to environmental and food toxins, known as xenobiotics . These chemicals are not usually present in the human body and are often associated with an increase in inflammation and an increased risk of cancer.
Most xenobiotic detoxification occurs in the liver in two stages. But, alas, we are so exposed to these toxins day after day that the liver is overloaded and functioning at a level below the optimum . Some plant foods help the body maintain natural detoxification rhythms and help the liver function properly, and turmeric is one of them. Other common products with detoxifying properties are cruciferous, garlic, onion, citrus peel (but not those citrus fruits from the supermarket that are processed!).
Eating turmeric can help the liver effectively detoxify the body and alleviate some of the dangerous effects of carcinogens.
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Turmeric and ancient medicine
Turmeric has been used in medicine for a very long time. The timeless principles of the practice of natural medicine in ayurveda and traditional Chinese medicine have largely led modern scholars to document the mechanisms of influence of valuable spices and herbs.
In traditional Chinese medicine and Ayurveda, doctors call turmeric a “warming spice”, but at first it has a “cooling” effect. Depending on which Ayurvedic dosha you belong to, the practitioner may prescribe you curcumin for long periods of time or for a short period.
Turmeric is often prescribed to patients with stagnation of blood and qi. These problems cause menstrual pain, trauma, enlargement of the liver and spleen, cirrhosis of the liver and coagulation disorders. Some doctors of Chinese medicine offer turmeric for conditions such as seizures, epilepsy, and mania. Since turmeric can “dry and cool” a “wet body,” it is also prescribed for jaundice and gallstones.
Since turmeric dilutes the blood, it is able to lower the pressure, so it is very useful for hypertensive patients.
Turmeric should be consumed with healthy fats for better digestion, such as coconut oil and black pepper.
Composition of turmeric
One spoon (or 7 grams) ground turmeric contains about:
23.9 calories;
4.4 grams of carbohydrates;
0.5 grams of protein;
0.7 grams of fat;
1.4 grams of fiber;
0.5 mg manganese (26% of the daily value);
2.8 mg of iron (16% of the daily value);
0.1 mg of vitamin B6 (6% of the daily value);
170 mg of potassium (5% of the daily value);
1.7 mg of vitamin C (3% of the daily value);
13 mg of magnesium (3% of the daily value).
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Frequent use of turmeric in cooking is a great way to get curcumin, but alas, about 3% of curcumin is absorbed from it, which is negligible. Along with adding turmeric to your diet, you may also consider taking it in the form of supplements that contain up to 95% of curcuminoids. Pay attention to dietary supplements, which include, in addition to curcuminoids, black pepper, which improves absorption.
Pay attention to fermented turmeric, as fermentation increases the presence of tetrahydracurcuminoids, which are particularly strong in the body . Unfermented turmeric is usually metabolized in the digestive system and creates tetrahydracurcuminoid compounds, but much of the potential at the time of metabolization may be lost.
Side effects
As mentioned above, turmeric has few side effects, they are rare and mild. An allergic reaction occurs most often. It manifests as a mild, itchy rash. Therefore, before taking turmeric, especially in the form of supplements, perform a home test for allergies. Start adding it in small quantities to dishes. In addition, high doses of turmeric can cause : nausea, diarrhea, increased risk of bleeding, hyperactive contractions of gall, hypotension, uterine contraction in pregnant women, increased menstrual cycle . ( 50 )
People taking certain medications should also be careful when using turmeric in food or supplements. Turmeric can interfere with anticoagulants, such as aspirin, clopidogrel and warfarin. It can also affect the effects of nonsteroidal anti-inflammatory drugs.
Pregnant women, people with gallbladder dysfunction, bleeding problems, diabetes, hormonal diseases (breast cancer, endometriosis, uterine myoma, etc.), men with problem fertility and people with iron deficiency also need to be careful with turmeric. As a rule, “being careful” means being under medical supervision. If you are a pregnant woman, set aside turmeric, especially in high doses, until the postpartum period.
As a rule, turmeric is safe in recommended doses for daily use for most people.
Stop taking turmeric two weeks before any planned surgery, as it potentially slows down blood clotting and can cause bleeding.
A study published in the journal Pharmacy and Pharmacology describes that the combination of turmeric with prednisone (a steroid) effectively reduces the side effects of this dangerous drug . Therefore, it may be helpful to discuss with your doctor about adding turmeric to your diet to mitigate the side effects of prednisone.
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