Monday, December 17, 2018

Side effects of biotin 10000


Side effects of biotin 10000

As I said in the previous article, Biotin for what it is and side effects , although biotin is a safe vitamin it is better to stick to the recommended dose, either on the label or following the instructions of your doctor.

During pregnancy and lactation biotin is safe, but if used in the recommended doses.


Diabetics should be careful, because biotin increases the production of glucose and fatty acids. It is necessary to consult with your doctor so that it does not exceed the recommended dose for your case.

People on dialysis may take additional doses, so you should talk with your health care provider.


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Side effects of biotin:

Diarrhea

Diarrhea could be a side effect of biotin, as well as stomach pain. If you have any of these symptoms, visit your doctor.


Allergies:


Some people may have an allergic reaction due to the intake of biotin supplements . These reactions are not very common, but there are probabilities. The person may feel nausea, swelling of the face or throat, rashes, chest pain. If this happens, you should go to emergencies immediately. But as I said earlier, the side effects of biotin are not frequent. In addition, there are people who are allergic, for example, to lemon and orange sawdust. Completely natural elements.

Cystic acne:


An excess of biotin can cause cystic acne on the chin and jaw. The reason why this type of acne is produced is not known, but it disappears within a few weeks of the suspension of the vitamin.


Abortion


Again, care should be taken with the high doses of biotin, as it could cause a pregnant woman to have a miscarriage. Although you do not have proof that confirms it, it is always good to consult with your doctor.


WARNING: Biotin is not recommended if you are ingesting anticonvulsants or medications indicated to reduce cholesterol levels. Biotin may reduce the effectiveness of these medications.

Biotin can be an ally to get healthy hair, skin and nails. However, you must take into account the recommendations set out in this article.

Biotin



Biotin

Summary
Water-soluble biotin is an essential cofactor for enzymes in intermediary metabolism and a key regulator of gene expression. (More information)
Both parenteral nutrition devoid of biotin and prolonged consumption of raw egg white have been associated with symptoms of frank biotin deficiency, including hair loss, dermatitis, and rash, ataxia, seizures, and other neurological dysfunctions.

Biotinidase deficiency is a hereditary disorder that impairs the absorption and recycling of biotin, resulting in a secondary biotin deficiency. (More information)
The recommended adequate intake (AI) of biotin is established at 30 micrograms (μg) / day in adults. The biotin requirements are more likely to increase during pregnancy and lactation period.

Studies in animals have shown that biotin sufficiency is essential for normal fetal development. If the marginal biotin deficiency during pregnancy increases the risk of congenital anomalies in humans, it is an area of ​​current concern and research.

Biotin is used in the treatment of a hereditary disorder of thiamine transport, called basal ganglia disease sensitive to biotin, and is currently being tested in trials to limit or reverse functional disabilities in people with multiple sclerosis. (More information)
The definitive evidence that establishes whether biotin supplementation improves the homeostasis of glucose and lipids in individuals with type 2 diabetes mellitus is currently scarce, but suggestive observations have been published.

Biotin can not be synthesized by mammalian cells and must be obtained from exogenous sources. Biotin is widely found in foods, and good dietary sources including egg yolks, liver, whole grain cereals, and some vegetables.

Long-term anticonvulsant (anti-seizure) therapy may increase the biotin dietary requirement because anticonvulsants may interfere with intestinal absorption and renal reabsorption of biotin and probably also increase the degradation of biotin to inactive metabolites.


Country Life Biotin 1000 mcg -100 Tablets



Biotin is a water-soluble vitamin that is generally classified as a B-complex vitamin. After its initial discovery in 1927, it took nearly 40 years of research to unequivocally establish biotin as a vitamin (1). Biotin is required by all organisms but can be synthesized by some strains of bacteria, yeast, fungi, algae, and some plant species (2).


Function
Biotinylation
Biotin functions as a covalently linked cofactor required for the biological activity of the five biotin-dependent carboxylase enzymes of mammals (see below). Such a non-protein cofactor is known as a "prosthetic group." The covalent attachment of biotin to apocarboxylase (ie, a catalytically inactive carboxylase) is catalyzed by the enzyme, holocarboxylase synthetase (HCS). The term "biotinylation" refers to the covalent addition of biotin to any molecule, including apocarboxylases and histones. HCS catalyzes the posttranslational biotinylation of the epsilon amino group of a lysine residue at the active site of each apocarboxylase, converting the inactive apocarboxylase into a fully active holocarboxylase (Figure 1a). Particularly the lysine residues within the N-terminus of specific histones, which help to package the DNA in the eukaryotic nucleus, can also be biotinylated (3). Biotinidase is the enzyme that catalyzes the release of biotin from biotinylated histones and the peptide products of holocarboxylase degradation (Figure 1b).


Enzyme cofactor
Five mammalian carboxylases that catalyze essential metabolic reactions:

Both acetyl-Coenzyme A (CoA) carboxylase 1 (ACC1) and acetyl-CoA carboxylase 2 (ACC2) catalyze the conversion of acetyl-CoA to malonyl-CoA using bicarbonate and ATP; malonyl CoA generated via ACC1 is a limiting substrate for the synthesis of fatty acids in the cytosol, and malonyl CoA generated via ACC2 inhibits CPT1, an enzyme of the outer mitochondrial membrane important in the oxidation of fatty acids (Figure 2). ACC1 is found in all tissues and is particularly active in lipogenic tissues (ie, liver, white adipose tissue, and mammary glands), the heart, and pancreatic islets. ACC2 is especially abundant in the skeletal muscle and heart (4).

Pyruvate carboxylase is a critical enzyme in gluconeogenesis - the formation of glucose from sources other than carbohydrates, such as pyruvate, lactate, glycerol, and glucogenic amino acids. Pyruvate carboxylase catalyzes the ATP-dependent incorporation of bicarbonate into pyruvate, producing oxaloacetate; hence, pyruvate carboxylase is anaplerotic for the citric acid cycle (Figure 3). The oxaloacetate can then be converted to phosphoenolpyruvate and eventually to glucose.

Methylcrotonyl-CoA carboxylase catalyses an essential step in the catabolism of leucine, an essential branched-chain amino acid. This enzyme containing biotin catalyses the production of 3-methylglutaconyl-CoA from methylcrotonyl-CoA (Figure 4a).
Propionyl-CoA carboxylase produces D-malonylmalonyl-CoA from propionyl-CoA, a product derived from the β-oxidation of fatty acids with an odd number of carbon atoms (Figure 4a). The conversion of propionyl-CoA to D-malonylmalonyl-CoA is also required in the catabolic pathways of two branched-chain amino acids (isoleucine and valine), methionine, threonine, and cholesterol side chain (Figure 4a and 4b) .


Regulation of chromatin structure and gene expression
In eukaryotic nuclei, DNA is packaged into compact structures to form nucleosomes - fundamental units of chromatin. Each nucleosome is composed of 147 DNA base pairs wrapped around eight histones (histone pairing: H2A, H2B, H3, and H4). Another histone, called H1 linker, is located on the outside surface of each nucleosome and serves as an anchor to fix the DNA around the nucleus of the histone. The compact packaging of the chromatin should be relaxed from time to time to allow biological processes, such as DNA replication and transcription. Chemical modifications of DNA and histones affect the folding of chromatin, increasing or reducing the accessibility of DNA to factors involved in the previously mentioned processes. Together with DNA methylation, a number of chemical modifications within the N-terminal end of the nucleus histones modify their electrical charges and structures, thereby changing the conformation of the chromatin and the transcriptional activity of the genes.

The various modifications of histone tails, including acetylation, methylation, phosphorylation, ubiquitination, SUMOylation, ADP-ribosylation, carbonylation, deimination, hydroxylation, and biotinylation, have different regulatory functions. Several biotinylation sites have been identified in the histones H2A, H3, and H4 (5). Among them, the biotinylation of histone H4 in lysine (K) 12 (designated H4K12bio) appears to be enriched in heterochromatin, a tightly condensed chromatin associated with repeat regions in the (peri) centromeres and telomeres, and with known transposable elements as long terminal repeats (3). In addition, biotinylation tags are co-localized with well-known repression marks of genes such as lysine 9 methylated on histone H3 (H3K9me) on transcriptionally competent chromatin (6). For example, H4K12bio can be found in the promoter of the SLC5A6 gene that codes for the transporter of the biotin assimilation mediation in cells, the human sodium-dependent multivitamin transporter (hSMVT). When biotin is abundant, HCS can biotinylate the histone H4 in the promoter of SLC5A6, which stops the synthesis of hSMVT and reduces the assimilation of biotin. Conversely, in the biotin-deficient cells, the biotinylation marks in the LC5A6 promoter are removed in such a way that gene expression can occur, allowing the synthesis of hSMVT and subsequently increasing the assimilation of biotin (7).


Deficiency
Although evident biotin deficiency is quite rare, the human biotin dietary requirement has been demonstrated in three different situations: prolonged intravenous (parenteral) feeding without biotin supplementation, infants fed an elemental formula lacking in biotin, and consumption of clear of raw egg for a prolonged period (from several weeks to several years) (8). Raw egg white contains an antimicrobial protein known as avidin that can bind to biotin and prevent its absorption. Cooking egg white denatures avidin, making it susceptible to digestion and therefore unable to prevent the absorption of biotin dietary (5).

Signs and symptoms of biotin deficiency
Signs of obvious biotin deficiency include hair loss (alopecia) and a reddish scaly rash around the eyes, nose, mouth, and genital area. Neurological symptoms in adults have included depression, lethargy, hallucinations, and numbness and tingling of the limbs, ataxia, and seizures. Characteristic facial eruptions, along with the unusual distribution of facial fat, have been called "biotin-lacking traits" by some researchers (1). Individuals with inherited disorders of biotin metabolism (see Congenital Metabolic Disorders) that result in functional biotin deficiency often have similar physical findings, as well as seizures and evidence of impaired function of the immune system and increased susceptibility to bacterial and fungal infections (9, 10).

Risk factors of biotin deficiency
Apart from prolonged consumption of raw egg white or total intravenous nutritional support lacking in biotin, other conditions may increase the risk of biotin depletion. Smoking has been associated with an increase in the catabolism of biotin (11). Rapidly dividing cells of the developing fetus require biotin for the synthesis of essential carboxylases and for the biotinylation of histones; therefore, the biotin requirement is prone to increase during pregnancy. Research suggests that a substantial number of women develop a marginal or subclinical deficiency during normal pregnancy (see also Disease Prevention) (8, 12, 13). In addition, certain types of liver diseases can decrease the activity of biotinidase and theoretically increase the biotin requirement. A study of 62 children with chronic liver disease and 27 healthy controls found that the activity of serum biotinidase was abnormally low in those with a severely impaired function due to cirrhosis (14). However, this study did not provide evidence of biotin deficiency. In addition, anticonvulsant medications, used to prevent seizures in individuals with epilepsy, increased the risk of a biotin depletion (for more information about biotin and anticonvulsants, see Drug / Drug Interaction).



Congenital metabolic disorders
Biotinidase deficiency
There are several ways in which hereditary disorder, biotinidase deficiency, leads to a secondary deficiency of biotin. Intestinal absorption is diminished because a shortage of biotinidase prevents the release of biotin from dietary proteins (15). The recycling of our own biotin bound to the carboxylase and histone is also altered, and the urinary loss of biocytin (N-biotinyl-lysine) and biotin is increased (see Figure 1 above) (5). The biotinidase deficiency uniformly responds to the supplemental biotin. Oral supplementation with up to 5 to 10 milligrams (mg) of biotin daily is sometimes required, although smaller doses are often sufficient (reviewed in 16).

Holocarboxylase synthetase (HCS) deficiency
Some forms of HCS deficiency respond to supplementation with pharmacological doses of biotin. HCS deficiency results in decreased formation of all holocarboxylases at physiological blood concentrations of biotin; thus, high-dose biotin supplementation (10-80 mg biotin daily is required (10).

The prognosis of these two disorders is usually good if biotin therapy is introduced early (childhood or childhood) and continues for life (10).

Deficiency of biotin transport
There has been a case report of a child with biotin transport deficiency who responded to a high-dose biotin supplementation (17). It should be noted that the presence of a defective human sodium-dependent multivitamin transporter (hSMVT) was discarded as the cause of biotin transport deficiency.

Phenylketonuria (FCU)
Abnormally high concentrations of the amino acid, phenylalanine, in the blood of individuals affected with FCU can inhibit the activity of biotinidase. Schulpis et al. he speculated that seborrheic dermatitis associated with low biotinidase activity in these patients would be resolved by compliance with a special diet low in protein but not with biotin supplementation (18).

Markers of biotin status
Four measures of marginal biotin deficiency have been validated as indicators of the status of biotin: (1) reduced urinary excretion of biotin and some of its catabolites; (2) the high urinary excretion of an organic acid, 3-hydroxyisovaleric acid, and its derivative, carnityl-3-hydroxyisovaleric acid, both of which reflect the decreased activity of the biotin-dependent methylcrotonyl-CoA carboxylase; (3) the reduced activity of propionyl-CoA carboxylase in peripheral blood lymphocytes (5); and (4) reduced levels of holo-methylcrotonyl-CoA carboxylase and holo-propionyl-CoA carboxylase in lymphocytes - the most reliable indicators of biotin status (19). These markers have only been validated in non-pregnant men and women, and may not accurately reflect the status of biotin in pregnant women and lactating women (12).

Adequate Intake (AI)
Sufficient scientific evidence is scarce to estimate the dietary requirement for biotin; therefore, a Recommended Daily Intake (IDR) for biotin has not been established. Instead, the Board of Nutrition and Food (JNA) of the Institute of Medicine (IOM) established recommendations for Adequate Intake (IA, Table 1). The AI ​​for adults (30 micrograms [μg] / day) was extrapolated from the AI ​​for infants exclusively fed with human milk and is expected to overestimate the dietary requirement for biotin in adults. Dietary intakes of generally healthy adults have been estimated to be between 40-60 μg / day of biotin (1). The requirement for biotin in pregnancy can be increased (20).



Disease Prevention
Congenital anomalies
Current research indicates that at least one third of women develop marginal biotin deficiency during pregnancy (8), but it is not known if this could increase the risk of congenital anomalies. Studies based on small observation in pregnant women have reported an abnormally high urinary excretion of 3-hydroxyisovaleric acid both early and late in pregnancy, suggesting a decreased activity of methylcrotonyl-CoA carboxylase dependent on biotin (21,22). In a randomized, single-blind intervention study in 26 pregnant women, supplementation with 300 μg / day of biotin for two weeks limited the excretion of 3-hydroxyisovaleric acid compared to placebo, confirming that the increased excretion of 3-hydroxyisovaleric acid in effect it reflected marginal biotin deficiency in pregnancy (23). A small cross-sectional study in 22 pregnant women reported an incidence of low activity of lymphocyte propionyl-CoA carboxylase (another marker of biotin deficiency) greater than 80% (13). Although the level of biotin deficiency is not associated with overt signs of deficiency in pregnant women, such observations are sources of concern because subclinical biotin deficiency has been shown to cause cleft palate and hypoplasia of limbs in several animal species (reviewed in 13). In addition, biotin depletion has been found to suppress the expression of biotin-dependent carboxylases, remove biotin tags from histones, and decrease proliferation in cultured human embryonic mesenchymal stem cells (24). The altered activity of carboxylases may result in alterations in lipid metabolism, which has been linked to cleft palate and skeletal abnormalities in animals. In addition, the biotin deficiency leading to the reduction of histone biotinylation at specific loci in the genome could possibly increase genomic instability and result in chromosomal abnormalities and fetal malformations (13).

While pregnant women are advised to consume supplemental folic acid before and during pregnancy to prevent neural tube defects (see Folate), it would also be prudent to ensure adequate intake of biotin during pregnancy. The current AI for pregnant women is 30 μg / day of biotin, and no toxicity has been reported at this level of intake (see Safety).



Treatment of Diseases
Biotin-sensitive basal ganglia disease
Biotin-sensitive basal ganglia disease, also called thiamin metabolism dysfunction syndrome-2, is caused by mutations in the gene encoding the thiamin type 2 transporter (THTR-2). Clinical features appear around three to four years of age and include subacute encephalopathy (confusion, drowsiness and altered level of consciousness), ataxia, and seizures. A retrospective study of 18 affected individuals from the same family or the same tribe in Saudi Arabia was recently conducted. The data showed that monotherapy with biotin (5-10 mg / kg / day) efficiently suppressed the clinical manifestations of the disease, although one third of patients suffered from recurrent acute crises. Often associated with poor outcomes, acute seizures were not observed after thiamin supplementation started (300-400 mg / day) and during a five-year follow-up period. An early diagnosis and immediate treatment with biotin and thiamin led to positive results (25). The mechanism for the beneficial effect of biotin supplementation has not yet been elucidated.

Multiple sclerosis
Multiple sclerosis (MS) is an autoimmune disease characterized by progressive damage to the myelin sheath surrounding the nerve fibers (axons) and neuronal loss in the brain and spinal cord of affected individuals. The progression of neurological disabilities in patients with MS is often assessed by the Expanded Disability Status Scale (EDSS) with scores from 1 to 10, starting with minimal signs of motor dysfunction (score of 1) to death by EM (score of 10). ATP deficiency due to mitochondrial dysfunction and increased oxidative stress may be partially responsible for the progressive degeneration of neurons in MS (26). Given its role in the intermediary metabolism and in the synthesis of fatty acids (required for the formation of myelin) (see Function), it has been postulated that biotin could exert beneficial effects that would limit or reverse functional alterations associated with MS (26) .

A non-randomized, uncontrolled pilot study in 23 patients with progressive MS found that high doses of biotin (100-600 mg / day) were associated with sustained clinical improvements in 5 (out of 5) patients with progressive visual loss and in 16 (from 18) patients with partial paralysis of the extremities after a mean follow-up period of three months after the start of treatment (27). In addition, preliminary results from the multicenter, randomized, placebo-controlled trial in 154 subjects with progressive MS indicated that 13 of 103 patients who randomly received daily oral biotin (300 mg) for 48 weeks achieved a composite functional endpoint that included a decrease in the scores of the EDSS. In comparison, none of the 51 patients randomly assigned to the placebo group showed significant clinical improvements (28). Two ongoing trials are evaluating the effect of high-dose biotin supplementation in the treatment of MS (see trials NCT02220933 and NCT02220244 at www.clinicaltrials.gov).





Mellitus diabetes
It has been shown that biotin deficiency manifests affects glucose utilization in mice (29) and causes fatal hypoglycemia in chickens. The biotin deficiency manifested probably also causes abnormalities in the regulation of glucose in humans (see Function). An early study in humans reported lower concentrations of serum biotin in 43 patients with type 2 diabetes mellitus compared to 64 non-diabetic control subjects, as well as an inverse relationship between fasting glucose and blood biotin concentrations (30). In a randomized, placebo-controlled intervention study in 28 patients with type 2 diabetes, daily supplementation with 9 milligrams (mg) of biotin for one month resulted in an average 45% decrease in fasting blood glucose levels (30 ). Nevertheless, another small study in 10 patients with type 2 diabetes and 7 non-diabetic controls found no effect of biotin supplementation (15 mg / day) for 28 days on fasting blood glucose concentrations in both groups ( 31). A more recent double-blind, placebo-controlled study by the same research group showed that the same biotin regimen decreased plasma triglyceride concentrations in both diabetic and non-diabetic patients with hypertriglyceridemia (32). In this study, the administration of biotin did not affect blood glucose concentrations in both groups of patients. Additionally, a few studies have shown that co-supplementation with biotin and chromium picolinate may be a beneficial adjunctive therapy for patients with type 2 diabetes (33-36). However, it has been shown that the administration of chromium picolinate alone improves glycemic control in diabetic subjects (see article in Chromium) (37).

As a cofactor of carboxylases required for the synthesis of fatty acids, biotin can increase the utilization of glucose for fat synthesis. It has been found that biotin stimulates glucokinase, a liver enzyme that increases the synthesis of glycogen, the stored form of glucose. Biotin also appears to trigger insulin secretion in the rat pancreas and improve glucose homeostasis (38). However, the reduced activity of ACC1 and ACC2 would be expected to reduce the synthesis of fatty acids and increase the oxidation of fatty acids, respectively. Not surprisingly, it is currently unclear whether biotin pharmacological doses could benefit the management of hyperglycemia in patients with impaired glucose tolerance. On the other hand, it remains to be proven whether supplemental biotin decreases the risk of cardiovascular complications in diabetic patients by reducing triglycerides and serum LDL cholesterol (32-34).




Brittle nails (onychorhexis)
The discovery that biotin supplements were effective in the treatment of hoof abnormalities in ungulate animals suggested that biotin might also be beneficial in strengthening brittle nails in humans (39-41). Three uncontrolled trials that examined the effects of biotin supplementation (2.5 mg / day for several months) in women with brittle nails have been published (42-44). In two of the trials, subjective evidence of clinical improvement was reported in 67% -91% of the participants available for follow-up at the end of the treatment period (42, 43). One trial that used scanning electron microscopy to evaluate the fragility of the nails reported less cracking of the nails and an increase in the thickness of 25% of the nail plate in patients supplemented with biotin for 6 to 15 months (44). It was also found that biotin supplementation (5 mg / day) was effective in controlling unruly hair and nail cracking in two young children with inheritable hereditary hair syndrome (45). Although preliminary evidence suggests that biotin supplementation may help strengthen fragile nails, larger placebo-controlled trials are needed to evaluate the efficacy of high-dose biotin supplementation for the treatment of brittle nails.

Hair loss (alopecia)
It was found that the administration of biotin reverses alopecia in children treated with the anticonvulsant, valproic acid (see Interaction with drugs / drugs). However, although hair loss is a symptom of severe biotin deficiency (see Deficiency), there are no published scientific studies supporting the claim that high-dose biotin supplements are effective in preventing or treating loss. of hair in men and women (46).




Sources
Food sources
Biotin is found in many foods, either as the free form that is directly taken by the enterocytes or as biotin bound to the dietary proteins. The yolk, liver, and yeast are rich sources of biotin. Estimates of the average daily biotin intakes from small studies ranged from 40 to 60 micrograms (μg) per day in adults (1). However, US national nutritional questionnaires have not yet been able to estimate the intake of biotin due to the scarcity and unreliability of the data with respect to the biotin content of the food. Food composition tables for biotin are incomplete so that daily intake can not be estimated reliably in humans. A study by Staggs et al. (47) used a high resolution liquid chromatography method instead of bioassays (48) and reported a relatively different biotin content for some of the selected foods. Table 2 lists some food sources of biotin, along with their content in μg.




Bacterial synthesis
Most bacteria that normally colonize the small intestine and the large intestine (colon) synthesize biotin (49). It remains unknown if biotin is released and absorbed by humans in significant quantities. Assimilation of free biotin in intestinal cells through the human sodium-dependent multivitamin transporter (hSMVT) has been identified in cultured cells derived from the lining of the small intestine and colon (50), suggesting that humans may be able to absorb biotin produced by enteric bacteria - a phenomenon documented in porcine.

Security
Toxicity
It is not known that biotin is toxic. In people without biotin metabolism disorders, doses of up to 5 mg / day for two years were not associated with adverse effects (52). Oral supplementation with biotin has been well tolerated in doses of up to 200 mg / day (almost 7,000 times the AI) in people with hereditary disorders of biotin metabolism (1). It was also found that daily supplementation with a highly concentrated formulation of biotin (100-600 mg) was well tolerated in individuals with progressive multiple sclerosis (27, 28). However, there is a case report of eosinophilic pleuropericardial effusion that endangers life in an elderly woman who took a combination of 10 mg / day of biotin and 300 mg / day of pantothenic acid (vitamin B5) for two months (53). Because reports of adverse events were scarce when the Dietary Reference Intakes (RDI) for biotin were established in 1998, the Institute of Medicine did not establish a maximum tolerable intake level (ML) for biotin (1).

Interaction with nutrients
Large doses of pantothenic acid (vitamin B5) have the potential to compete with biotin for intestinal and cellular uptake by the human sodium-dependent multivitamin transporter (hSMVT) (54, 55). Biotin also shares hSMVT with α-lipoic acid (56). It has been found that pharmacological (very high) doses of α-lipoic acid decrease the activity of biotin-dependent carboxylases in rats, but such an effect has not been demonstrated in humans (57).

Interaction with drugs
Individuals on long-term anticonvulsant (anti-seizure) therapy have reportedly reduced blood levels of biotin as well as increased urinary excretion of organic acids (eg 3-hydroxyisovaleric acid) indicating a decrease in the carboxylase activity (see Markers of biotin status) (5). The potential mechanisms of biotin depletion by anticonvulsants, primidone (Mysoline), phenytoin (Dilantin), and carbamazepine (Carbatrol, Tegretol), include inhibition of intestinal absorption and renal reabsorption of biotin, as well as catabolism increased biotin (51). The use of anticonvulsant valproic acid in children has resulted in hair loss reversed by biotin supplementation (58-61). Long-term treatment with antibacterial sulfonamide drugs (sulfa) or other antibiotics may decrease the bacterial synthesis of biotin. However, given that the extent to which bacterial synthesis contributes to the intake of biotin in humans is not known, the effects of antimicrobial drugs on the status of nutritional biotin remain uncertain (51).




Recommendation of the Linus Pauling Institute
Little is known about the amount of biotin dietary required to promote optimal health or prevent chronic diseases. The Linus Pauling Institute supports the recommendation made by the Institute of Medicine, which is 30 micrograms (μg) of biotin per day for adults. A varied diet should provide enough biotin for most people. However, following the recommendation of the Linus Pauling Institute to take a multivitamin-mineral supplement daily will generally provide an intake of at least 30 μg / day of biotin.

Older adults (> 50 years old)
Currently, there is no indication that older adults have an increased biotin requirement. If biotin dietary intake is not enough, a multivitamin-mineral supplement daily will generally provide an intake of at least 30 μg of biotin per day.

Sunday, December 16, 2018

Can I take prenatal vitamins and biotin?

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Can I take prenatal vitamins and biotin?

Having a healthy diet and good nutrition is a major concern for many pregnant women. A maternal diet that is rich in vitamins and nutrients will help in the prevention of congenital defects and will provide the developing young with the resources they need to grow. In addition, vitamins such as biotin can protect the mother from some of the adverse side effects of pregnancy, including hair loss. Always consult your health care provider before taking any new supplement or medication, or combine more than one of these.

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About prenatal vitamins
Prenatal vitamins are often prescribed by doctors for a pregnant woman to meet the nutritional demands of their developing child. Vitamins and minerals such as iron, folic acid and B vitamins are important for fetal growth and maternal health and may not be available in a sufficient number of dietary sources. Prenatal vitamins are available with and without a prescription. Keep in mind that not all prenatal vitamins are the same, some contain a higher dose of one vitamin and a lower dose of another. Ask your doctor to help you choose a supplement that meets your unique needs.

About biotin
Biotin, also known as vitamin B7 or vitamin H, is available in some dietary sources and participates in the functioning of various enzymes in the body. Symptoms of biotin deficiency include hair loss and a red, scaly rash on the face. Other symptoms include tiredness, hallucinations, depression and tingling sensation in your extremities.

Biotin and pregnancy
The change in hair growth and distribution is a common symptom of pregnancy. Most women notice a head more completely covered with hair during pregnancy since circulating hormones prevent normal hair loss. Three months after the birth of your child, all the hair accumulated during pregnancy will fall all at once, or for several weeks. Although it is alarming, hair loss is normal and your hair will return to its pre-pregnancy state within six to twelve months. The American Pregnancy Association suggests that using shampoos containing biotin or taking biotin supplements orally can reduce hair loss after your pregnancy.

Recommendations
While the use of biotin is considered safe during pregnancy and is available without a prescription, you should consult your doctor before taking any new supplements. Your prenatal vitamin can already contain biotin and the vitamin should not be taken in excess. The best source of vitamin B7 and other nutrients is a healthy diet. Biotin is found in cauliflower, yeast, egg yolk, liver, avocado, raspberries, salmon, pork, wholemeal bread and cheddar cheese.

Biotin tablets for your health

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Biotin tablets for your health

You've probably heard about biotin, but you do not know what it is. Biotin is a vital vitamin for the organism of any human being since this vitamin is responsible for metabolizing carbohydrates, fats and amino acids.

Similarly biotin is also known as vitamin b8, b7 or vitamin H, responsible for converting glucose into calories, maintaining very healthy tissue cells such as hair, skin and nails; Biotin is also responsible for the creation of hemoglobin.


Thanks to all these favorable properties biotin is used in various treatments including type II diabetes, seborrheic dermatitis and especially in recipes for hair with biotin, is used in shampoos and pills to counteract hair loss and weakness.

Benefits of biotin
Biotin has been used for many years in shampoos for horses, currently has increased its use in human shampoo since it is aiding in problems of hair loss and problems such as dandruff.

It is very rare to have a deficit of biotin in the body, however in the cases that this occurs, the nervous system and the hair are affected by the skin; In recent years the birth of babies with biotin deficiency has increased due to problems related to prematurity and nutritional deficits. These problems of biotin deficiency can manifest with muscle aches, vomiting, lack of muscle mass or sores in the mouth.


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Where is Biotin?
We get many foods with biotin of vegetable or animal origin, such as liver and beef viscera, brewer's yeast, egg yolk, some fish such as salmon and sardine also contain significant amounts of biotin and are low in fat ; In the same way, dairy products and nuts, such as nuts.

The recommended contribution of biotin for children under 12 years ranges between 10 micrograms and 30 micrograms. After that age it is recommended to increase the biotin contribution between 30 and 110 micrograms.



Biotin for hair
Biotin helps to grow and strengthen hair Biotin is famous for all the properties it has to improve the health of our hair, for being a vitamin that strengthens and gives more shine to hair. Due to this in recent years has proliferated all types of hair treatments with biotin. The most common way of these hair treatments are shampoos with biotin, also known as shampoo for horses, but various scientific studies have shown that the effectiveness of biotin in these methods is very low and almost zero. Which does not mean that biotin does not help improve the appearance and health of our hair, on the contrary for biotin to be effective in these treatments must be ingested through biotin supplements or through a diet with food intake that They contain this important vitamin as mentioned above.

Symptoms and common signs of Biotin deficiency

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Symptoms and common signs of Biotin deficiency

Biotin (biotin, biothin) is a vitamin belonging to the B complex, is water soluble which means that our body does not have the ability to store it and therefore must be taken daily. It is known by many names: vitamin B8, vitamin H, biotin and vitamin B7. It has the property of linking several enzymes that are essential in the processes of cellular duplication, and therefore is used in cell growth, in the production of fatty acids, and in the metabolism of fat and amino acids.

Although it is one of the most rare nutrient deficiencies, without a doubt you could at some point present a lack or deficiency of biotin. Since the body does not store biotin due to its water-soluble characteristic, its consumption must be continuous.


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Symptoms of Biotin deficiency
Pregnant women are among the groups most at risk of missing or deficient biotin, which has been shown to have adverse effects on the development of fetuses.

Without a doubt, biotin is an essential vitamin for the organism. Many times we do not identify when we have a deficit of some type of vitamin or mineral, so it is very important to know the signs of lack of biotin in the body.

The red and scaly rash (especially on the face) plus hair loss are common signs that your body may need more biotin.

Biotin deficiency symptoms and signsOther symptoms and signs of biotin deficiency are:
Depression.

  • Sickness.
  • Loss of appetite
  • Paresthesia
  • Muscle pain.

In the body, biotin plays a very important role in:
The metabolism of fats, amino acids and carbohydrates.

  • The optimal function of the nervous system.
  • Maintaining the healthy level of LDL cholesterol.
  • Regulation of sugar in the blood

Strengthening the hair and reversing the loss by reacting with the enzymes to generate amino acids, which are fundamental for proteins such as keratin, from which the hair is made

  • Prevent deterioration or cognitive dysfunction related to age
  • Keep a healthy skin
  • The strengthening of the nails. In one study, 2.5 mcg of biotin per day for at least 6 months improved its thickness by 25%.



Biotin tests
Currently there are tests that are performed to detect exactly how our biotin levels are in the blood, but these tests are indicated under very special conditions, such as preterm infants, among others. In an Internet survey we detect that they are done in specialized laboratories and have a cost of around $ 300.

In Venezuela they do biotin tests for free in the IDEA, but it has to be indicated by a specialist, until now we do not know where else they do it.



What is biotin and how is it used for beard?

High Potency Biotin USP (D-Biotin) 100mg (100,000mcg)

What is biotin and how is it used for beard?

Greetings friends, in this opportunity we will teach you several aspects about biotin for our beard, I will explain with details what the hell is, what things you should not do and also how to consume it.

All this information comes from an arduous investigation of several sources and after an own experience using several brands and doses of biotin, so it can serve as a guide and not make fatal mistakes like ingesting menoxidil accompanied by absurd amounts of biotin as recommended by several foristas of internet, thing for nothing recommendable and counterproductive. But we begin to educate ourselves.


High Potency Biotin USP (D-Biotin) 100mg (100,000mcg)


What is biotin for beard?
There is not really a product like "Biotin for beard", it is simply biotin and it is a vitamin that starts from the group of the B complex, it is also known as vitamin H and as vitamin B7, why? because the same complex is part of it.

Biotin is an essential vitamin in our body and as mentioned, is not exclusively beard, in fact its main function is to increase metabolism, keep nails and hair healthy, combat hair loss helping to generate the Keratin and also helps to have healthy skin.

Particularly dry skin and people with type II diabetes receive treatments with high doses of biotin.

You should also bear in mind that this vitamin, is not permanent in the body, is continuously discarded through the urine.

 If you have a healthy diet, biotin is constantly ingested so it would not seem logical to ingest it separately, however having a very healthy diet with the necessary contributions of biotin in these days of constant speed and running is quite complicated

What foods provide biotin?
There is no doubt that the Latin diet is very rich in biotin, as we have pointed out in other posts about foods that contain biotin, this is very different from the average diet of an American who tends to eat more processed and transgenic food, most of them Latinos have a more traditional diet that includes cereals, fruits, vegetables, fish, etc.

Biotin can be found in foods such as almonds, eggs, sardines, strawberries, bananas, carrots, onions, mushrooms, soybeans, nuts, etc ... As you can see, it is very possible that you consume this vitamin frequently.



If you want to know how to organize a diet rich in biotin, read this article.


What about biotin pills?
First you must understand that if you are going to ingest biotin pills, you must know how to use them and measure them for a correct benefit.

  • Biotin for adults is commonly sold in concentrations of 30 mcg.
  • PENDING is not the same mg as mcg!
  • The mcg means microgram, 1000 microgram is 1 gram; The recommended daily dose for an adult is 30 MICROgrams.
  • Some trade unionists say that you should consume 10,000 mcg and sometimes up to 20,000 mcg to get a good beard.

It is an exaggeration, inform yourself well before affecting your health by mere vanity.

Keep in mind that the biotin that your body does not need, is going to be discarded in the urine. High doses of biotin are recommended only under medical supervision.

The multi-vitamins designed for the growth of the beard have 3000 mcg of biotin at most and tell you explicitly that consuming 3000 mcg of biotin is 1000% of your recommended daily dose.



Another thing before consuming biotin.
Brother, biotin will not give the desired results if not ingest with green leaves in your diet and you swallow it along with the first meal of the day ... not when you paste that wins effects.

Beware of biotin!
Brother, forget about using biotin if you're taking anti-cholesterol or anti-seizure medications. If you are diabetic, do not even think about consuming biotin.

Frequent questions.
Does biotin help against baldness?
No, biotin will help make existing hair (from anywhere) not fall, but it does not help the generation of new hair, for that we use Minoxidil.

Do biotin shampoos work?
There are those who say yes and others say no.

The truth is a very controversial issue and to this day I am still investigating this matter.

Some say that biotin can not be absorbed through the skin and others say that shampoos with biotin have helped them to grow their hair faster.

All this came out of the fact that they began to recommend shampoos for horses to people with weak and brittle hair but their results are inconclusive.

I think people who say that biotin does work for you is more a mental fact than true verifiable results.

What is the recommended dosage?
As I mentioned earlier, the recommended daily dose for an adult man is 30 micrograms.

Is there something to replace biotin for beard?
Here I must ask, replace it for what purpose? if the growth of beard, you can search stimulants containing jojoba oil, castor oil, eucalyptus and / or rosemary oils as our beard also I recommend you use a shampoo for free beard salts and sulfates.

The salts and sulphates pull and weaken the hair, eye with those beard shampoos that contain these ingredients.

  • If you are looking to swell your beard, this publication may be useful.
  • In a nutshell
  • Ingesting biotin will do you good, but do it consciously, ingesting large amounts of foolishness will not accelerate the growth of your beard.

Remember that the lack of beard is not considered a disease so there are no reliable medical sites that recommend the use of biotin as a treatment to grow the beard.

As I always recommend more use of natural products and as they say the trade of alcohol, all with measurement and the next time someone tells you that sells biotin beard does wonders, you can give a good kick in the butt and ask you to report well before.



Properties and benefits of Biotin

Bulksupplements Pure Biotin (Vitamin B7) Powder (25 grams)

Properties and benefits of Biotin

biotin capsules for hair

Vitamin H also known as biotin, vitamin B7 and vitamin B8 all refer to a water soluble vitamin B group. Biotin promotes normal growth and development and helps maintain good health in general. It is necessary for the metabolism of carbohydrates, proteins and fats. resulting in the production of energy. It also helps in the formation of fatty acids and supports cell growth. Other very significant pharmacological effects of biotin include better management of diabetes and its prevention, lower blood lipid content and regulation of metabolism.


Bulksupplements Pure Biotin (Vitamin B7) Powder (25 grams)



Biotin helps treat alopecia (hair loss) and premature aging in individuals with extremely low levels of biotin. If you have a biotin deficiency and also suffer from abundant hair loss, you can get positive results just by meeting your daily biotin needs. It is also ideal against muscle pain and anemia.

Adequate intake promotes brain health and has been shown to be an adjuvant to prevent neurological problems such as hallucinations and sensations of tingling in the extremities. Even more, it is compatible with the production of fat, which contributes to a healthy-looking skin (our skin is supported by fatty tissue)

According to the Journal of Nutritional Biochemestry (a specialized publication on biochemistry) the intake of supplements with biotin can help blood lipid levels and contribute to better control of diabetes because the vitamin promotes both hyperglycemia and hyperlipidemia .


Biotin deficiency can cause very unpleasant health problems and can lead to more serious problems at the neurological level. Alopecia (partial or total loss of hair), seborrheic dermatitis, anemia, muscle aches, nausea, fatigue, loss of appetite, conjunctivitis, even episodes of depression, hallucinations, numbness and tingling in the hands and feet are all symptoms of biotin deficiency.

Undoubtedly it is of vital importance for good health and here we present the 10 benefits of biotin or vitamin H


  • 1. It is necessary for the production of growth of cells and fatty acids.
  •  
  • 2. Participate in the production of energy by metabolizing fat, proteins and carbohydrates
  •  
  • 3. Play a key role in the krebs cycle (process of releasing energy from food).
  •  
  • 4. Ensures healthy skin
  •  
  • 5. Prevents premature aging
  •  
  • 6. Avoid hair loss
  •  
  • 7. Reduce muscle pain
  •  
  • 8. Promotes healthy sweat glands, nerve tissue and bone marrow.
  •  
  • 9. Supports the transfer of carbon dioxide at the cellular level
  •  
  • 10. Maintains constant blood sugar levels


As you can see biotin is of great importance for good health, considering that it offers many benefits. Daily needs can be easily met through a balanced diet containing biotin-rich foods such as yeast, eggs, fish, salmon, tuna, cod, nuts such as peanuts, and lots of healthy green leafy vegetables like spinach



Foods with biotin

High Potency Pure Biotin 5000 mcg for Hair Growth (5mg) - 60 Count

Foods with biotin

11 foods that contain more biotin

There are many foods that contain vitamin H also known as biotin and are excellent sources of this vitamin, among some are the kidneys, liver, milk, eggs, soy beans, and several vegetables and many fruits such as cambur, the milky, bananas, spinach and tomatoes. Also nuts like almonds and walnuts contain a lot of biotin.

Numerous foods of plant origin have biotin in its free form. In foods of animal origin and yeast, biotin must be separated through the process of digestion so that the body can absorb it in its entirety and take advantage of it.

Suffering from biotin deficiency does not happen very often, but not having enough can affect your hair and skin leading to a non-optimal condition. Getting enough biotin can also mean increased metabolism, balanced blood glucose levels, and it's just one of the B vitamins you do not want to be away from too long. Luckily, it's quite easy to include it in the menu and replace it, and you will be very far from that small statistic that has a biotin deficit.


High Potency Pure Biotin 5000 mcg for Hair Growth (5mg) - 60 Count
High Potency Pure Biotin 5000 mcg for Hair Growth (5mg) - 60 Count


1. Mushrooms
Mushrooms are a healthy food in general, as they contain many properties in minerals and vitamins, but in particular if you are distressed by your biotin levels, you may want to be sure to include mushrooms in your meals, or lean more towards them. Menu dishes that include them. Besides being a high source of biotin, it brings with it a mixture of nutrients and very healthy minerals for various areas of the body, and should not be overlooked as a very healthy food. It is advisable to try different types of mushrooms to see which is the most pleasing, each of these contemplate several flavors but all equally very nutritious.

Recommended portion of mushrooms: 100 grams 38 calories, 19% of the RDA of iron, contains 1 mg of biotin.


2. Tuna
Tuna is very rich in biotin, and also has a lot of other benefits such as omega-3 and more vitamins that make it a very valuable food for human health, so its inclusion in the diet is recommended at least twice. a week. It is also not recommended to abuse their consumption, since tuna may contain small traces of mercury from the seas where they are caught, so it is not advisable to consume very frequently, especially the Pacific Ocean. Tuna is also well known for being a great source of protein and omega-3, as well as all the benefits this has on humans.

Recommended portion of Tuna: 100 grams, 184 calories, supply of vitamin B12 full day, contains 1.7 mg of biotin



3. Turkey meat
Turkey is an excellent source of protein to help build a large muscle mass, but it is also a great source of biotin; and this is one of the reasons why the vast majority of Americans do not suffer from biotin deficiency. While you and I are sticking to the boneless and turkey breast skin that has been toasted while cooking the piece makes it maintain your body fat and helps increase it, making it part of a very healthy diet. healthy. That is why you will see turkey included in some of the most popular diet plans around the world.

Recommended portion of turkey meat: 100 grams, 104 calories, 18g protein, contains 2.1 mg of biotin.



4. Avocados
Avocados are full of so many vitamins, minerals and other healthy things like protein and fiber, which is not surprising that you can use it to get some biotin by adding it to the menu. They provide a good portion of healthy fat, as well, both monounsaturated and polyunsaturated, so it does not matter how you eat it, in a recipe, in a divine salad, or on your own, as this will give you a good nutritional contribution to your health.

5. Chard
Chard is often eclipsed by green leafy vegetables such as kale and super spinach, however it is a very healthy vegetable and can help maintain your optimal biotin levels. In addition to its already known contribution of vitamin A, it is also full of magnesium, fiber and vitamin C. It is a very beneficial vegetable for you that you can easily include in your menu in shakes and salads to have a better health.

Recommended portion of chard: (100 grams), 19 calories, vitamin A supply, contains 1.8 mg of biotin.



6. Eggs
The debate continues on whether eggs are good for health or not. Some say they are, some say no, and another go back and forth about the healthiness of the yolk compared to the clear one. But one thing is certain, and that is that eggs provide you with biotin, so if you are interested in increasing your levels you may consider eating them. They also provide protein and other nutrients, as well as cholesterol.

Recommended portion of eggs: (100 grams), 155 calories, 13g proteins, contains 1.9 mg of biotin.



7. Salmon
Salmon is often praised for its high levels of proteins and omega-3 fatty acids, and it is a very successful thing since 20% of 100 gr of protein. It is common to see salmon used in sushi rolls, and it is also used as Main dish, which is served with a serving of broccoli or asparagus, as well as basmati rice or quinoa make a full meal. Many health experts suggest eating salmon several times a week for its anti-inflammatory properties and its contribution of biotin.

Recommended portion of salmon: 100 grams, 208 calories, 20g protein, contains 1.1 mg of biotin.



8. Sunflower seeds
This bite is one of the favorites on the baseball field and is actually a great source of minerals such as magnesium, and vitamins such as biotin or vitamin H. Preferably eat them raw so you will avoid the added fat and calories that come with sunflower seeds dry toast Buying organic seeds is also a good idea, since conventional seed agriculture involves the use of a lot of chemicals.

Recommended portion of sunflower seeds: 100 grams, 584 calories, 81% of the magnesium CDR, contains 1.3 mg of biotin.



9. Liver
Eating liver meat is not the same as eating beef, since it has many more mineral loads in it, as well as additional vitamins, depending on the cut. What you can be sure of is that you are getting a good intake of biotin when you eat liver. It is also a rich source of magnesium and iron, but perhaps not as high a contribution of the latter as does a piece of beef. Visiting a butcher shop may be your best bet if you want to increase your biotin levels.

Recommended portion of liver: 100 grams, 516 calories, total fat 4g, contains 1.8 mg of biotin.


A delicious contribution of biotin

10. Peanut butter
If you like the taste of peanut butter you will be happy to know that it is helping to meet your biotin needs. It is full of protein, but it can also provide a large amount of calories in just a small amount. In his book The ABS Diet, author David Zinczenko lists peanut butter as a superfood and shows how to incorporate more into a healthy diet, using it as a tasty additive to nutritious smoothies.
Recommended serving of peanut butter: 100 grams, 589 calories, 24g protein, contains 1.6 mg of biotin.

All cheeses provide biotin

11. Cheese
Cheese is usually excluded from diet plans because of its high content of fat, sodium and cholesterol. When consumed in moderation, it can be a good source of biotin, as well as being high in calcium and vitamin B12. While it is better not to exaggerate the consumption of cheese, sometimes it can be difficult to avoid it since it manifests itself in many recipes and menu items.

Recommended portion of cheese: 100 grams, 402 calories, full day calcium supply, contains 1.4 mg of biotin.
Since biotin is a water-soluble vitamin, it is not recommended to cook vegetables for a long time, so it is recommended to drink only boiled water during the intake of biotin.
Surely you know many more foods that contain biotin, share them with us in your comments, how do you combine these foods to get a contribution of biotin to your diet?



Breastfeeding and biotin

Biotin 5000 PLUS - 7X More Effective For Hair, Skin and Nails - Complete Anti Aging Formula - Collagen and...

Breastfeeding and biotin

You can take pregnant biotin When a newborn comes home, the mother will need all the energy she can get to be fully active for her care, and biotin will be of great help. Biotin, or vitamin H, is a coenzyme that is responsible for digesting carbohydrates, fats and proteins, and contributes to the conversion of food into energy. It is also vital for the health of hair, skin and eyes, as well as the liver and the efficient functioning of the nervous system. Biotin deficiency is rare, but pregnancy makes you more susceptible to your condition. No doubt you need more of this potent nutrient during your lactation period so that you and your baby are completely healthy.

Signs of a biotin deficiency
Biotin is a water-soluble vitamin, which means that it is soluble in water. This is not preserved in the body but is expelled through your urine and sweat. Not having adequate amounts in the body can generate signs of deficiency. According to MedlinePlus, there is no precise test to detect a biotin deficiency (beyond specific tests in specialized laboratories), but your doctor must recognize it for its symptoms, which include thinning hair and a scaly rash on the face. The intake of biotin is also required to have a healthy nervous system, and without enough you can develop exhaustion, depression, hallucinations and tingling in the arms and legs.


Biotin 5000 PLUS - 7X More Effective For Hair, Skin and Nails - Complete Anti Aging Formula - Collagen and...
Biotin 5000 PLUS - 7X More Effective For Hair, Skin and Nails - Complete Anti Aging Formula - Collagen and...


Breastfeeding and Biotin Compatible?
Recommendations and Sources
Some studies indicate that adults and pregnant women need around 32 micrograms of biotin daily. For lactating women, the recommended daily amount is 35 micrograms. Biotin may be taken during breastfeeding as long as it is prescribed by your doctor. Biotin is found naturally in various foods, such as in brewer's yeast, egg yolk, nuts, beans, black-eyed peas, whole grains, Swiss chard, bananas and mushrooms. It depends on the type of preparation that these foods have, biotin may decrease in it, it is recommended little cooking or ingestion in a natural way to avoid killing biotin. Do your best to eat enough food to satisfy your levels and your baby can have all the benefits of breastfeeding and biotin, but if you have a deficit it is best to talk to your doctor to tell you to take a supplement .

Biotin in breast milk
During breastfeeding, not only biotin is excreted in the urine, it is also passed to the baby through breast milk, so the recommended dose is higher for mothers who are breastfeeding. According to the CHILEAN INSTITUTE OF REPRODUCTIVE MEDICINE (ICMER), breast milk contains variable amounts of biotin. The more you breastfeed your baby, the more biotin you put into the milk. The amount of biotin is also directly linked to the amount of biotin in the blood, but the amount in the milk is hundreds of times greater than the amount in the blood.

Milk crust and biotin
Vitamin for the milk crust - biotin Biotin can be very useful in the treatment of the milk crust in babies. Although this is totally harmless, the milk crust forms a flaky, dry skin on your baby's scalp. You might also notice thick yellow or brown scaly patches that scale on the head or around your ears, eyebrows, eyelids and armpits. This condition should disappear on its own at 12 months of age, but a biotin supplement can be taken to hasten its disappearance. NYU Langone Medical Center recommends that breast-feeding mothers take a biotin supplement to treat the milk crust or care for your baby's brittle hair and nails. Check with your doctor before adding any supplements to your diet.



Biotin is important for hair health


Biotin is important for hair health

A recent research from Harvard University shows that among the factors that make biotin important for hair health, it is found that it metabolizes fatty acids and amino acids that play a key role in hair loss.

Because hair strands consist largely of a protein called keratin, the metabolism of amino acids (the compounds that make all proteins), is essential for the production of beautiful and healthy hair.

Biotin is known as a vitamin B complex that helps nourish hair follicles. Therefore, biotin deficiency can decrease the development of the cells that make up the hair follicles. Although these cases are rare; They can develop in people who consume large amounts of alcohol and maintain a diet poor in nutrients.


Thorne Research - Biotin 8 - Vitamin B7 (Biotin) for Healthy Hair, Nails, and Skin - 60 Capsules
Thorne Research - Biotin 8 - Vitamin B7 (Biotin) for Healthy Hair, Nails, and Skin - 60 Capsules



Biotin reduces hair loss
Biotin deficiency causes an abnormal metabolism of fatty acids, which influences hair loss, hair break without explanation, fragility and, splitting of hair strands. When the hair becomes unhealthy, it becomes brittle, they break easily and tend to fall out. By taking biotin, you can maintain the health of the scalp and reduce hair loss.

According to the American Pregnancy Association, some women may develop hair loss during and after pregnancy, and biotin can cope with this problem.

Alopecia or hair loss can have a devastating impact on a person's mental health. Biotin has been used to treat both children and adults who suffer from alopecia. In the fight against diseases such as alopecia, biotin is the most effective when used in combination with topical clobetasol propionate together with zinc.

Experts suggest that taking about 5 mg of biotin under the supervision of a doctor helps prevent hair loss. In addition to the oral intake of biotin supplements to cope with hair loss, topical products are currently available for use.

Biotin helps strengthen and beautify your hair Biotin strengthens and grows hair
Biotin and hair growth are closely related. It is effective in promoting hair to grow faster and faster (healthy hair will allow each strand to reach the end of its growth cycle without breakage and less damage).

This vitamin helps hair grow, but the results may be different for each person, especially if it is not taken continuously. On the other hand, you have to understand that although biotin is useful, you will not see the difference overnight. It takes about a month or more to improve the length of the hair. Even if your hair does not grow quickly after using it, you still get some other benefits for eyelashes and nail growth.

The hair follicle is found in the dermis and plays a major role in the maintenance of the stem cells, which make the hair grow back in case it falls. When the hair follicles are blocked with the scales of the skin, they prevent the process of hair growth. Meanwhile, biotin helps with dry and scaly scalp that could cause hair loss.

For people suffering from hair loss and hair fragility, additional doses of biotin can make hair grow longer, thicker, and totally healthy.




Biotin prevents dry hair
Biotin increases the elasticity of the hair cortex, helping to prevent hair loss, as well as minimizing hair breakage. It also helps in the anagen and categen phase since they provide more sustainable nutrients.

On the other hand, it nourishes the scalp, dermis, epidermis, and helps the body to absorb the B vitamins, which are very important for hair.

Tips for optimal hair growth when taking biotin
  • Drink plenty of water to stay hydrated
  • When biotin is ingested, or anything in general, your body aims to take it down, and this requires a large amount of water. Since biotin is a water-soluble vitamin, it is necessary to consume a large amount of water per day (6-8 glasses per day) to make the biotin dissolve easily and not bring out the skin buds. In addition to helping with hydrolysis, it is also essential for the roots to obtain a good amount of water saturation for hair growth.

Biotin can be ingested in supplementsUse a supplement
Ingesting biotin from food is great, but it's a bit difficult to trace. Selecting a supplement that contains biotin is the most effective way to absorb biotin and will also control the levels you have consumed. It is a simple and fast method, so take a pill a day and wait for the result.

Get other vitamins and minerals
Biotin is one of the many things you can take to accelerate hair growth and support healthy and strong hair growth. There are other good hair supplements on the market that combine many nutrients that the body needs for healthy hair growth.

Decrease alcohol consumption
Alcohol decreases the amount of biotin your body receives and also damages vitamin B that the body naturally produces. If you hope to maintain all the benefits of biotin for healthy hair growth, simply decrease or eliminate alcohol consumption for one month while taking biotin.

Biotin is ideal for hair growth Is biotin an ideal treatment for hair loss and for the new growth plan?


Biotin and hair growth are closely related. As I mentioned earlier, biotin deficiency can be associated with hair loss (which can lead to an abnormal metabolism that is likely to cause hair loss); Therefore, it is necessary to keep the level of biotin in your body high enough if you want to have thick hair. If you do not get enough biotin, you may even lose your eyebrows and eyelashes.

Biotin is essential especially for skin cells and their cell proliferation, which is why it is an effective tool in hair growth. Many people may think that skin and hair do not relate to each other, but in reality skin cells play a key role in the health of the hair follicles. Weak hair follicles do not have the ability to retain hair, which causes hair loss. Improving the health of the hair follicles is a good way to produce healthy hair growth. In addition, biotin increases the elasticity of the bark of a hair; therefore, it prevents and minimizes hair breakage. For those who are having problems with hair loss, taking extra biotin can make hair grow longer, thicker and healthier.

Hair is made up of keratin - a form of protein. When you eat foods that contain biotin, this vitamin reacts with enzymes in your cells and helps produce amino acids, which build protein blocks.

Combine biotin with vitamins for hair loss and it will have fantastic effects on both hair growth efforts and the prevention of hair loss. But if it is combined with vitamin B, the result seems to be much higher.




What is biotin (Appearex)?

Nutricost Biotin (Vitamin B7) 10,000mcg, 240 Capsules - Gluten Free, Non-GMO

What is biotin (Appearex)?

Biotin is a form of vitamin B, present in many foods and available as a supplement.

Biotin is sold under many names, including Appearex, vitamin B7, vitamin H, biotin, biotin and coenzyme R.

Many multivitamins and vitamin B supplements also contain biotin.

Biotin works by breaking down food into sugar that your body can use for energy.

Biotin is important for the health of the skin and nails, and also keeps the eyes, liver and nervous system functioning properly.

During pregnancy, biotin is important for normal fetal development.

Biotin is not stored in the body. Because of this, you can reduce biotin if you do not get enough in your diet.

Although biotin deficiency is rare, it can develop during pregnancy or in people who have poor nutrition or experience rapid weight loss.

Symptoms of biotin deficiency include hair loss, dry skin, scaly rash around the eyes or mouth, dry eyes, fatigue and depression.

Many people take biotin supplements in the hope of treating hair loss, cradle infants and brittle nails.

Some people also take biotin supplements to treat diabetes and nerve pain associated with diabetes, although there is not much evidence to support this type of use.

Some research also suggests that a deficiency in nutrients that include biotin might contribute to the development of type 2 diabetes.


Nutricost Biotin (Vitamin B7) 10,000mcg, 240 Capsules - Gluten Free, Non-GMO
Nutricost Biotin (Vitamin B7) 10,000mcg, 240 Capsules - Gluten Free, Non-GMO

Two studies in 2012 found that biotin improved blood sugar and insulin levels in people with type 2 diabetes when taken together with chromium supplements.

The researchers concluded that taking biotin supplements can be beneficial for both people with diabetes and those who are obese.

Biotin for hair
Biotin is a popular supplement for hair, skin and nails, although there is little evidence to suggest that taking biotin supplements can stop hair loss or stimulate hair or nail growth.

Similarly, the use of biotin shampoo or other hair products is unlikely to produce any benefit.

There is some evidence that taking biotin supplements with other medications can help control the hair loss associated with childhood alopecia.



Biotin warnings
Always check with your doctor before taking any supplement. Some conditions and medications can cause low levels of biotin.

Tell your doctor if you are:

  • On dialysis
  • Smoking cigarettes
  • Eat two or more raw egg whites a day
  • Take medicine for seizures
  • I have been on a long-term antibiotic course
  • Biotin is a safe vitamin that is unlikely to cause side effects.

However, before taking biotin supplements, tell your doctor if you are pregnant, can become pregnant, or if you are breast-feeding.







Side effects of biotin

If you want to have hair as long as Rapunzel's, you've probably heard about biotin, biotin shampoo, biotin scalp treatments and the biotin supplements that become more popular and difficult every day to avoid in terms of treatments to grow your hair in question, since its main promise is to give you thick and healthy hair ..

Because of its ubiquity, it seems to be an opportune time for a definition: Biotin (also known as vitamin B7 or vitamin H) belongs to the group of B vitamins. It is found in foods such as egg yolk, salmon and vegetables from green leaf, and also occurs naturally in our body by intestinal bacteria. Our organisms do not really require a lot of biotin to get by, but since it plays a role in cell growth, it is cataloged as a way to lengthen the hair and strengthen the nails.

Lately it has become very popular and many people trust it blindly; It's like a secret formula that is supposed to help you have long and healthy hair in an almost magical way. Those who have tried it or have consumed it can tell how their experience has been, but looking at it from a scientific point of view, it is not proven that the body needs more biotin than it produces.


As evidenced in a study done in Into the Gloss, taking it in supplements does not hurt, but it can produce some side effects of biotin if you give more doses to your body than you really need.


Biotin can cause acne? Biotin: Contraindications
Some dermatologists still recommend biotin, since it is not harmful to take it mainly because of its water-soluble characteristic. It is not really designed for people without biotin deficiency, so "there is no consensus on the dose of biotin for hair and nails health," says Dr. Jessica Weiser, a board-certified dermatologist for the Dermatology Group New York. "However, the most commonly suggested dose is 2,500 mcg or 2.5 mg a day."

Some of those contraindications of biotin is acne. As Dr. Jessica Weiser says, consuming more vitamins than we need can produce an imbalance that weakens the protective layer of the skin.

This layer is what prevents environmental substances from entering the pores easily, and therefore, the one that protects us from pimples and blackheads.

"Both biotin and pantothenic acid (vitamin B5) are absorbed from the intestines through the same receptors," he explained. "By taking biotin supplements, the amount of biotin in the intestine is much greater than the amount of vitamin B5, which leads to a relative deficiency of vitamin B5. Pantothenic acid is believed to regulate the barrier function of the surface layer on the skin and can reduce acne lesions. Therefore, a deficiency of pantothenic acid or excess biotin could lead to acne lesions. "




Excess biotin
If excess biotin is ingested, there will be an imbalance of vitamin B5, and skin imperfections will be more likely to appear on the face. In any case, each organism works differently, and it may be helpful for some people to take biotin for hair, and not experience the side effects of biotin.

In simpler terms, you could be giving yourself a B5 deficiency by consuming too much biotin, and that is what is causing your skin to deteriorate and generate acne.

Biotin Causes Obesity Dr. Jessica J. Krant, a board-certified dermatologist at the New York Center for Laser and Skin Surgery, has heard about these side effects of biotin, too. "Many reports indicate that excess ingested biotin can lead to rashes and acne breakouts," he said. "You do not have to be a great scientist or do a lot of scientific research and placebo-controlled trials to prove this, but if you start taking biotin and your acne gets worse, biotin may actually be the culprit."

Your solution? Stop taking the blessed biotin. "I have personally stopped recommending it to patients with nail or hair problems," said Dr. Krant. "If someone asks me about it, I explain that I am not against it, but only help a few people in rare, specific cases."

On the other hand, if you are seeing improvements in hair or nail health when taking biotin (just because there are no scientific studies to back it up, does not mean it is impossible), you do not have to give up taking it. Dr. Weiser suggests taking vitamin B5, along with biotin, to restore balance and avoid the possible side effects of taking biotin. Or you could simply wait for your hair to grow naturally.

Anyway, if you have a tendency to have acne problems and you want to try biotin, it is better to consult a doctor who will know how to advise you in the best way.