Source Naturals Magnesium Malate 1250mg Per Serving Essential Magnesium Malic Acid Supplement - 360 Tablets
Magnesium through the eyes of a neurologist
The name "magnesia" is found already in the Leiden papyrus X (III century AD). It comes probably from the name of the city of Magnesia in the mountainous region of Thessaly. The magnesian stone in ancient times was called magnetic iron oxide, and magnes - magnet. Interestingly, the original name "magnesium" was preserved only in Russian thanks to the Hess textbook, and at the beginning of the 19th century in a number of manuals other names were suggested - magnesia, magnesia, and bitter soils.
The total magnesium content in humans is about 25 grams. It plays an important role in the formation of more than three hundred enzymes. Magnesium takes part in energy and electrolyte metabolism, acts as a regulator of cell growth, is necessary at all stages of the synthesis of protein molecules. Particularly important is the role of magnesium in membrane transport processes. Magnesium helps to relax muscle fibers (muscles of blood vessels and internal organs). The most important value of magnesium is that it serves as a natural anti-stress factor, inhibits the processes of excitation in the central nervous system and reduces the body's sensitivity to external influences.
It is believed that in 25-30% of the population magnesium is insufficiently supplied with food. This may be due to modern processing technologies and the use of mineral fertilizers in growing vegetables, leading to a magnesium deficiency in the soil.
Chronic magnesium deficiency is often noted in patients with diabetes, hypertension, atherosclerosis, epilepsy, osteoporosis, etc. A number of physiological states are known that are accompanied by an increased need for magnesium: pregnancy, breastfeeding, a period of intensive growth and maturation, old and old age, hard physical labor and physical exercise in athletes, emotional stress, frequent and long-lasting (more than 30-40 minutes per session) stay in the sauna, lack of sleep, air travel and the intersection of time zones. Magnesium deficiency occurs when taking caffeine, alcohol, drugs and some drugs, such as diuretics, which help remove magnesium from the urine.
Our nervous system is sensitive to the level of magnesium in the body. Its lowered content can cause anxiety, nervousness, fear, as well as insomnia and fatigue, decreased attention and memory, in some cases - convulsive seizures, tremors and other symptoms. Often people complain of "gratuitous" headaches.
Magnesium (especially in combination with vitamin B6) has a normalizing effect on the state of the higher parts of the nervous system during emotional stress, depression, and neurosis. This is not by chance. Stress (physical, mental) increase the need for magnesium, which is the cause of intracellular magnesium deficiency.
Magnesium deficiency worsens with age, reaching a maximum in people over 70 years old. According to the European epidemiological study of cardiovascular diseases, plasma magnesium levels below 0.76 mmol / l are considered as an additional risk factor for stroke and heart attack (for example, for arterial hypertension). The imbalance of Ca2 + and Mg2 + ions is one of the serious reasons for the formation of blood clots in the vessels. The use of magnesium preparations helps to reduce the tendency to form a blood clot. Magnesium, for example, enhances the antithrombotic effect of aspirin.
It is believed that magnesium plays a positive role, slowing down the process of atherosclerosis.
Considering the latest data on the prevalence of magnesium deficiency among residents of large cities, its content in the blood is determined in neurological patients with chronic fatigue syndrome, vegetative-vascular dystonia, as well as in depression and asthenia. Normally, the content of magnesium in the blood serum in children varies from 0.66 to 1.03 mmol / l, in adults from 0.7 to 1.05 mmol / l.
In healthy people, the daily need for magnesium is 350-800 mg. When magnesium deficiency requires its additional introduction at the rate of 10-30 mg per kilogram of body weight per day. In addition to dietary correction, medicinal preparations are also used. The saturation time of tissue depots during magnesium therapy is 2 months or more. The choice of drugs for correction is well known - these are inorganic and organic salts of magnesium. The first generation of magnesium-containing preparations included inorganic salts. However, in this form magnesium is absorbed by no more than 5%, stimulates intestinal motility, which often leads to diarrhea. Magnesium absorption in the gastrointestinal tract increases lactic, pidolovaya and orotic acids, vitamin B6 (pyridoxine), some amino acids.
The second generation of magnesium-containing drugs is much better absorbed and does not cause dyspepsia and diarrhea. Magne-B6 is a modern combination drug.
Magne-B6's anti-anxiety effect allows it to be included in the complex therapy of depression (together with antidepressants), convulsive states (in combination with anticonvulsants), sleep disorders (together with hypnotics), and also to use the drug as an additional means for preventing and leveling the lungs effects of brain metabolism activators. Magnesium therapy is quite a promising direction in the treatment of night sleep disorders of various origins, especially in patients with asthenic and anxiety states. The vasodilating effect of magnesium ions allows the use of Magne-B6 in combination with antihypertensive agents. However, a decrease in blood pressure in response to the administration of magnesium is achieved only in patients with magnesium deficiency.
Magne B6 is usually well tolerated without causing any side effects. Normalization of the magnesium level in the human body in combination with other drugs allows to achieve success in many diseases of the nervous system, it is now considered as a classic metabolic therapy.
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